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Early detection of Alzheimer's disease: From multiplex assays and imaging to point of care devices and AI-based functional monitoring

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机构: [1]German Center for Neurodegenerative Diseases (DZNE) Rostock, Rostock, Germany [2]Department of Psychosomatic Medicine, University Medicine Rostock, Rostock, Germany [3]Department of Neurology, Center for Alzheimer Research and Treatment, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA [4]Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA [5]Faculty of Science and Engineering, University of Plymouth, Plymouth, UK [6]Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China [7]CoBTek (Cognition-Behaviour-Technology) Lab, Université Côte d’Azur, Nice, France [8]ki:elements GmbH, Saarbrücken, Germany [9]Centre Hospitalier et Universitaire, Clinique Gériatrique du Cerveau et du Mouvement, Centre Mémoire de Ressources et de Recherche, Université Côte d’Azur, Nice, France
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关键词: Alzheimer’s disease artificial intelligence biomarkers deep learning digital technology health care imaging markers multi-domain biomarkers

摘要:
The advent of disease-modifying treatments and risk-reduction strategies in the clinic have increased the demand for biomarkers for early disease detection, prediction of clinical course of disease, individual risk prediction and monitoring of treatment effects. The studies in this special issue span ultra-sensitive fluid assays and automated laboratory platforms, structural and molecular neuroimaging, electrophysiology, digital cognitive and behavioral monitoring, multi-omics, neuromodulation, and the computational frameworks necessary to integrate these diverse data.

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出版当年[2025]版:
大类 | 3 区 医学
小类 | 3 区 神经科学
最新[2025]版:
大类 | 3 区 医学
小类 | 3 区 神经科学
第一作者:
第一作者机构: [1]German Center for Neurodegenerative Diseases (DZNE) Rostock, Rostock, Germany [2]Department of Psychosomatic Medicine, University Medicine Rostock, Rostock, Germany
通讯作者:
通讯机构: [1]German Center for Neurodegenerative Diseases (DZNE) Rostock, Rostock, Germany [2]Department of Psychosomatic Medicine, University Medicine Rostock, Rostock, Germany
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