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Specialty Balloons Versus Plain Old Balloon Angioplasty for Vessel Preparation Before Drug-Coated Balloon Therapy in Femoropopliteal Occlusive Disease

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资源类型：
Pubmed体系：
作者：
Wang Xinyuan[1] * ; Ye Meng[2] * ; He Chunshui[3] ; Fang Xin[4] ; Wu Ziheng[5] ; Li Qiang[6] ; Shi Weihao[7] ; Shi Zhenyu[8] ; Guo Lianrui[9] ; Feng Zibo[1] ;
机构： [1]Department of Vascular Surgery, Liyuan Hospital affiliated Tongji Medical College of Huazhong University of Science & Technology, Wuhan, China [2]Department of Vascular Surgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China [3]Department of Vascular Surgery, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China [4]Department of Vascular Surgery, Affiliated Hangzhou First People’s Hospital, Zhejiang University School of Medicine, Hangzhou, China [5]Department of Vascular Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China [6]Department of Vascular Surgery, The Affiliated Qingdao Hiser Hospital of Qingdao University, Qingdao, China [7]Department of Vascular Surgery, Huashan Hospital, Fudan University, Shanghai, China [8]Department of Vascular Surgery, Zhongshan Hospital, Fudan University, Shanghai, China [9]Department of Vascular Surgery, Xuanwu Hospital, Capital Medical University, Beijing, China
出处：
DOI： 10.1016/j.amjcard.2025.09.054
ISSN：

关键词： Vessel preparation specialty balloon drug-coated balloon leave nothing behind real-world femoropopliteal occlusive disease peripheral artery disease

摘要：
Specialty balloons are a novel category of vessel preparation devices. This study compared their effectiveness and safety with plain old balloon angioplasty (POBA) in a real-world setting. A total of 1,574 patients who underwent drug-coated balloon (DCB) therapy for femoropopliteal occlusive disease at ten Chinese centers (2021-2023) were analyzed. Propensity score matching generated 434 balanced pairs. Compared with POBA, specialty balloons were associated with a lower stent implantation rate (19% vs 28%; P = 0.003), shorter median stent length (15 cm vs 19 cm; P = 0.017), and use of larger-diameter DCB (4.9 ± 0.5 mm vs 4.8 ± 0.6 mm; P < 0.001). Perioperative complications, ankle-brachial index, hospital stay, and 1-year outcomes-including clinically driven target lesion revascularization, major amputation, mortality, and composite endpoints-did not differ between groups. In the overall cohort, 26% required stenting. Independent predictors of stent implantation were chronic total occlusion, smoking, moderate-to-severe calcification, and greater lesion length, while specialty balloon use was protective. In conclusion, compared with POBA, specialty balloon demonstrated superior vessel preparation outcomes, manifesting as significantly reduced stent implantation requirements, shorter average stent length, and enabling the use of larger-diameter DCB.Copyright © 2025 Elsevier Inc. All rights reserved.

基金：
Intramural Research Program of Liyuan Hospital, Tongji Medical College, Huazhong University of Science and Technology (NO. 2023LYYYKYPT0001)
语种：
外文
PubmedID：
中科院(CAS)分区：
出版当年[2025]版：
大类 | 3 区 医学
小类 | 4 区 心脏和心血管系统
最新[2025]版：
大类 | 3 区 医学
小类 | 4 区 心脏和心血管系统
第一作者：
第一作者机构： [1]Department of Vascular Surgery, Liyuan Hospital affiliated Tongji Medical College of Huazhong University of Science & Technology, Wuhan, China
共同第一作者：
通讯作者：
通讯机构： [*1]Department of Vascular Surgery, Liyuan Hospital affiliated Tongji Medical, Hubei Provincial Clinical Research Center for Chronic Wound and Diabetic Foot
推荐引用方式(GB/T 7714)：
Wang Xinyuan,Ye Meng,He Chunshui,et al.Specialty Balloons Versus Plain Old Balloon Angioplasty for Vessel Preparation Before Drug-Coated Balloon Therapy in Femoropopliteal Occlusive Disease[J].The American Journal Of Cardiology.2025,doi:10.1016/j.amjcard.2025.09.054.
APA：
Wang Xinyuan,Ye Meng,He Chunshui,Fang Xin,Wu Ziheng...&Feng Zibo.(2025).Specialty Balloons Versus Plain Old Balloon Angioplasty for Vessel Preparation Before Drug-Coated Balloon Therapy in Femoropopliteal Occlusive Disease.The American Journal Of Cardiology,,
MLA：
Wang Xinyuan,et al."Specialty Balloons Versus Plain Old Balloon Angioplasty for Vessel Preparation Before Drug-Coated Balloon Therapy in Femoropopliteal Occlusive Disease".The American Journal Of Cardiology .(2025)

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