机构：[a]Department of Neurology, Sir Run Run Shaw Hospital of Zhejiang University School of Medicine, Zhejiang, China[b]Department of Neurology, The Second Affiliated Hospital of Suzhou University, Jiangsu, China[c]Department of Neurology, Ruijin Hospital of Shanghai Jiao Tong University School of Medicine, Shanghai, China[d]Department of Neurology, The First Affiliated Hospital of Anhui Medical University, Anhui, China[e]Department of Neurology, The First Affiliated Hospital of Fujian Medical University, Fujian, China[f]Department of Neurology, Nanjing Brain Hospital, Nanjing Medical University, Jiangsu, China
Primary focal or segmental dystonia is a rare clinical condition. The clinical features of dystonia have not been evaluated in China. We performed a study to investigate the epidemiology of primary dystonia and its clinical variants in an adult population.
A Botulinum Toxin Clinic-based study was conducted in the period 18 May through 8 October 2010 in East China. We identified 523 dystonia patients from the Movement disorders and Botulinum Toxin clinic Cases.
The most common focal dystonia were blepharospasm (59%), cervical dystonia (35%), limb dystonia (3%), oromandibular dystonia (2%) and laryngeal dystonia (1%). Males with primary dystonia were noted to have earlier age of onset. A female predominance was noted for most of the primary dystonias with a male to female ratio (M : F) ranging from 1 : 1.48 to 1 : 3.
The epidemiological features of dystonia in East China we collected were similar to the report in Japan which contrasts partly with that reported in Europe.
第一作者机构：[a]Department of Neurology, Sir Run Run Shaw Hospital of Zhejiang University School of Medicine, Zhejiang, China
通讯作者：
通讯机构：[*1]Department of Neurology, Sir Run Run Shaw Hospital of Zhejiang University School of Medicine, 6 Qingchun East Road, Hangzhou, Zhejiang, China
推荐引用方式(GB/T 7714)：
Li Wang,Xingyue Hu,Chunfeng Liu,et al.Botulinum toxin clinic-based epidemiologic survey of adults with primary dystonia in East china.[J].Journal of movement disorders.2012,5(1):9-13.doi:10.14802/jmd.12003.
APA：
Li Wang,Xingyue Hu,Chunfeng Liu,Yiwen Wu,Changqing Wang...&Jun Chen.(2012).Botulinum toxin clinic-based epidemiologic survey of adults with primary dystonia in East china..Journal of movement disorders,5,(1)
MLA：
Li Wang,et al."Botulinum toxin clinic-based epidemiologic survey of adults with primary dystonia in East china.".Journal of movement disorders 5..1(2012):9-13
