机构：[a]Department of Neurology, Huashan Hospital, Fudan University, Shanghai, China[b]Institute of Neurology, WHO Collaborating Center for Research and Training in Neurosciences, Huashan Hospital, Fudan University, Shanghai, China[c]Department of Neurology, Ningxia Medical University Affiliated Hospital, Yinchuan, China[d]Jiaozuo People’s Hospital, Jiaozuo, Henan, China[e]Jincheng Emergency Center, Shanxi Province, China[f]Department of Neuroscience, Monash University, Alfred Hospital, Melbourne, Victoria, Australia[g]Beijing Neurosurgical Institute, Capital Medical University, Beijing, China研究所北京市神经外科研究所首都医科大学附属天坛医院[h]NIHR University College London Hospitals Biomedical Research Centre, UCL Queen Square Institute of Neurology, Queen Square, London, WC1N 3BG, United Kingdom[i]Chalfont Centre for Epilepsy, Chalfont St Peter, SL9 0RJ, United Kingdom[j]Stichting Epilepsie Instellingen Nederland (SEIN), Achterweg 5, Heemstede, 2103 SW, the Netherlands
Purpose: We evaluated the oral health and dental status of people with epilepsy, and their relationship to seizure frequency, in a community cohort in rural China. Methods: A cross-sectional study of people with epilepsy was carried out in areas in Henan, Shanxi and Ningxia provinces of China. All participants underwent a specially designed "Oral health and Dental status Questionnaire". Univariate and multivariate analyses were used to explore the relationships between seizure frequency and oral health and dental status. Results: A total of 875 people participated. Almost two thirds (65.8%) reported brushing their teeth at least once a day but 634 (73.0%) brushed their teeth for less than 3 min each time. Only 80 (9.1%) had visited a dental clinic in the previous year. Multivariate logistic regression analysis showed that having 1-4 seizures/month (OR 0.60, 95%CI 0.40-0.90) or > 4 seizures/month (OR 0.38, 95%CI 0.22-0.66) was associated with decreased odds of brushing teeth at least once a day, and higher seizure frequency was associated with increased odds of dental injury due to seizures (OR 2.07, 95%CI 1.22-3.50 for < 1 seizure/month; OR 2.12, 95%CI 1.25-3.58 for 1-4 seizures/month; OR 3.09, 95%CI 1.57-6.07 for > 4 seizures/month). Conclusion: Seizure frequency was significantly associated with seizure-related dental injury, and with the lack of good oral health practice. Improvement in the oral health of people with epilepsy in resource-poor areas should be encouraged.
基金：
UK Department of Health's National Institute for Health Research Biomedical Research Centers funding schemeNational Institute for Health Research (NIHR); Dr. Marvin Weil Epilepsy Research Fund; UK Epilepsy Society; Key Research Project of the Chinese Ministry of Science and Technology [2016YFC0904400]; NIH/NINDS grant [1R21NS069223-01]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China [81271443]
第一作者机构：[a]Department of Neurology, Huashan Hospital, Fudan University, Shanghai, China
通讯作者：
通讯机构：[a]Department of Neurology, Huashan Hospital, Fudan University, Shanghai, China[b]Institute of Neurology, WHO Collaborating Center for Research and Training in Neurosciences, Huashan Hospital, Fudan University, Shanghai, China[c]Department of Neurology, Ningxia Medical University Affiliated Hospital, Yinchuan, China[*1]Huashan Hospital, 12 Middle Wulumuqi Rd., Shanghai 200040, China[*2]General Hospital of Ningxia Medical University, 804 Shengli N Street, Yinchuan, Ningxia Hui Autonomic Region, 750004, China.
推荐引用方式(GB/T 7714)：
Mengjie Wang,Ding Ding,Qing Zhang,et al.Oral health and dental status in people with epilepsy in rural China[J].SEIZURE-EUROPEAN JOURNAL OF EPILEPSY.2019,65:42-47.doi:10.1016/j.seizure.2018.12.022.
APA：
Mengjie Wang,Ding Ding,Qing Zhang,Guoxing Zhu,Yan Ge...&Josemir W. Sander.(2019).Oral health and dental status in people with epilepsy in rural China.SEIZURE-EUROPEAN JOURNAL OF EPILEPSY,65,
MLA：
Mengjie Wang,et al."Oral health and dental status in people with epilepsy in rural China".SEIZURE-EUROPEAN JOURNAL OF EPILEPSY 65.(2019):42-47
