CD147 is a widely expressed integral plasma membrane glycoprotein and has been involved in a variety of physiological and pathological activities in combination with different partners, including cyclophilins, caveolin-1, monocarboxylate transporters, and integrins. Recent data demonstrate that both CyPA and CD147 significantly contribute to renal inflammation, acute kidney injury, renal fibrosis, and renal cell carcinoma. Here we review the current understanding of cyclophilin A and CD147 expression and functions in kidney diseases and potential implications for treatment of kidney diseases.
基金：
National Natural Science Foundation of ChinaNational Natural Science Foundation of China [81372473]; China Postdoctoral Science FoundationChina Postdoctoral Science Foundation [2014M550766]
第一作者机构：[1]Shandong Univ, Shandong Prov Hosp, Dept Crit Care Med, Jinan 250021, Peoples R China;[2]Capital Med Univ, Beijing Tiantan Hosp, Dept Crit Care Med, Beijing 100050, Peoples R China;
通讯作者：
通讯机构：[2]Capital Med Univ, Beijing Tiantan Hosp, Dept Crit Care Med, Beijing 100050, Peoples R China;[3]Capital Med Univ, Beijing Tiantan Hosp, Dept Crit Care Med, 6 Tiantan Xili, Beijing 100050, Peoples R China
推荐引用方式(GB/T 7714)：
Qu Xin,Wang Chunting,Zhang Jicheng,et al.The Roles of CD147 and/or Cyclophilin A in Kidney Diseases[J].MEDIATORS OF INFLAMMATION.2014,2014:-.doi:10.1155/2014/728673.
APA：
Qu, Xin,Wang, Chunting,Zhang, Jicheng,Qie, Guoqiang&Zhou, Jianxin.(2014).The Roles of CD147 and/or Cyclophilin A in Kidney Diseases.MEDIATORS OF INFLAMMATION,2014,
MLA：
Qu, Xin,et al."The Roles of CD147 and/or Cyclophilin A in Kidney Diseases".MEDIATORS OF INFLAMMATION 2014.(2014):-
