机构:[1]Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China临床科室心脏内科中心首都医科大学附属安贞医院[2]Beijing Anzhen Hospital, Capital Medical University, Beijing, China首都医科大学附属安贞医院[3]The Key Laboratory of Remodeling-Related Cardiovascular Diseases, Capital Medical University, Ministry of Education, Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing, China首都医科大学附属安贞医院[4]Department of Ultrasound, Beijing Jishuitan Hospital, Beijing, China
Background Left bundle branch area pacing (LBBaP) is a new physiological pacing strategy that produces comparable clinical effects to His bundle pacing (HBP). Objective The purpose of this study was to investigate the immediate clinical outcomes of LBBaP vs RVP. Methods and Results From April 2018 to September 2018, we included 44 patients under continuous pacemaker implantation. Patients were randomly divided into the LBBaP group and conventional RVP group. Compared to the RVP group, the LBBaP group displayed significantly increased operative (90.10 +/- 19.68 minutes vs 61.57 +/- 6.62 minutes, P < .001) and X-ray exposure times (15.55 +/- 5.62 minutes vs 4.67 +/- 2.06 minutes, P < .001). The lead threshold of the LBBaP group was increased (0.68 +/- 0.20 mV vs 0.51 +/- 0.0 mV, P = .001), while the R-wave amplitude and ventricular impedance did not significantly differ between the two groups. The conventional RVP procedure significantly widened the QRS complex (93.62 +/- 8.28 ms vs 135.19 +/- 12.21 ms, P = .001), whereas the LBBaP had no effect on QRS complex (130.13 +/- 43.30 ms vs 112.63 +/- 12.14 ms, P = .904). Furthermore, the LBBaP procedure significantly narrowed the QRS complex in patients with left bundle branch block (LBBB) (168.43 +/- 38.870 ms vs 119.86 +/- 6.69 ms, P = .019). Conclusion LBBaP is a new physiological, safe and effective pacing procedure with a high overall success rate. Compared to conventional RVP, LBBaP can correct LBBB, thereby improving cardiac electrical dyssynchrony.
基金:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China
第一作者机构:[1]Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China
通讯作者:
通讯机构:[1]Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China[*1]Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
推荐引用方式(GB/T 7714):
Zhang JunMeng,Wang Zefeng,Cheng Liting,et al.Immediate clinical outcomes of left bundle branch area pacing vs conventional right ventricular pacing[J].CLINICAL CARDIOLOGY.2019,42(8):768-773.doi:10.1002/clc.23215.
APA:
Zhang, JunMeng,Wang, Zefeng,Cheng, Liting,Zu, Linna,Liang, Zhuo...&Wu, Yongquan.(2019).Immediate clinical outcomes of left bundle branch area pacing vs conventional right ventricular pacing.CLINICAL CARDIOLOGY,42,(8)
MLA:
Zhang, JunMeng,et al."Immediate clinical outcomes of left bundle branch area pacing vs conventional right ventricular pacing".CLINICAL CARDIOLOGY 42..8(2019):768-773