当前位置: 首页 > 详情页

Twenty-five year outcomes following composite graft aortic root replacement

文献详情

资源类型:

收录情况: ◇ SCIE

机构: [1]Yale Univ, Sch Med, Aort Inst Yale New Haven, Clin Bldg CB317,789 Howard Ave, New Haven, CT 06519 USA; [2]Capital Med Univ, Beijing Inst Heart Lung & Blood Vessel Dis, Beijing Anzhen Hosp, Dept Cardiovasc Surg, Beijing, Peoples R China; [3]Kazan State Med Univ, Dept Surg Dis 2, Kazan, Russia
出处:
ISSN:

摘要:
BACKGROUND: Operative choices for aortic root disease include traditional root replacement with a composite valved graft as well as various valve-sparing and root repair procedures. OBJECTIVES: To report our experience with traditional composite graft aortic root replacement by a single surgeon over a 25-year period in 449 patients, focusing on long-term survival and freedom from late reoperation and adverse events. METHODS: The coronary button technique was used in all patients. Mean age was 56.1 +/- 14.0 years (range 14-87) with 83% males (373/449). Valve prosthesis was mechanical in 343 (76%) and bioprosthetic in 106 (24%). A modified Cabrol procedure (Dacron coronary graft) was employed in 10% (45/449) and concomitant coronary artery bypass graft in 10.9% (49/449). There were 15.8% (71/449) urgent/emergent and 8.2% (37/449) redo procedures. Survival follow-up was 100%. Mean follow-up was 7.0 +/- 5.1 years (range 0.1-24.8). RESULTS: Operative mortality occurred in 14 patients (3.1%) and was 2.2% (9/418) in non-dissection and 1.9% (7/361) in elective first-time operations. Stroke and re-exploration for bleeding occurred in nine (2.0%) and 20 (4.5%) patients, respectively. Major late events included bleeding in 2.5% (11/435) and thromboembolism in 1.1% (5/435). At 5, 10, and 20 years, freedom from major events and reoperations on the root were 97.8, 95.4, and 94.39%, and 99.0, 99.0, and 97.9%, respectively. Survival in patients aged <60 years was 92.0, 90.1, and 79.8% at five, 10, and 20 years versus 88.4, 67.9, and 42.6% in patients aged >= 60 years (p = 0.001). Compared with age-and gender-matched controls, survival was not significantly different (p = 0.20). CONCLUSIONS: Composite graft aortic root replacement is associated with low operative risk, excellent long-term survival, and low incidence of reoperation and late events.

语种:
被引次数:
WOS:
PubmedID:
中科院(CAS)分区:
出版当年[2016]版:
大类 | 4 区 医学
小类 | 4 区 心脏和心血管系统 4 区 外科
最新[2025]版:
大类 | 4 区 医学
小类 | 4 区 心脏和心血管系统 4 区 外科
JCR分区:
出版当年[2015]版:
Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Q4 SURGERY
最新[2024]版:
Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Q3 SURGERY

影响因子: 最新[2024版] 最新五年平均 出版当年[2015版] 出版当年五年平均 出版前一年[2014版] 出版后一年[2016版]

第一作者:
第一作者机构: [1]Yale Univ, Sch Med, Aort Inst Yale New Haven, Clin Bldg CB317,789 Howard Ave, New Haven, CT 06519 USA;
通讯作者:
通讯机构: [1]Yale Univ, Sch Med, Aort Inst Yale New Haven, Clin Bldg CB317,789 Howard Ave, New Haven, CT 06519 USA;
推荐引用方式(GB/T 7714):
APA:
MLA:

资源点击量:18307 今日访问量:0 总访问量:1007 更新日期:2025-11-01 建议使用谷歌、火狐浏览器 常见问题

版权所有©2020 首都医科大学宣武医院 技术支持:重庆聚合科技有限公司 地址:北京市西城区长椿街45号宣武医院