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Effect of Remote Ischemic Preconditioning in the Elderly Patients With Coronary Artery Disease With Diabetes Mellitus Undergoing Elective Drug-Eluting Stent Implantation

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收录情况： ◇ SCIE

作者：

机构： [1]Capital Med Univ, Beijing Inst Heart Lung & Blood Vessel Dis, An Zhen Hosp, Dept Cardiol, Beijing 100029, Peoples R China; [2]Capital Med Univ, Sch Rehabil Med, China Rehabil Res Ctr, Beijing 100029, Peoples R China; [3]Capital Med Univ, Beijing Inst Heart Lung & Blood Vessel Dis, An Zhen Hosp, Dept Cardiol, Anzhenli Ave, Beijing 100029, Peoples R China

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关键词： remote ischemic preconditioning elderly diabetes mellitus drug-eluting stent high sensitivity cardiac troponin I myocardial infarction type 4a

摘要：

There is conflicting evidence regarding the effectiveness of remote ischemic preconditioning (RIPC) in patients undergoing elective percutaneous coronary intervention (PCI). Therefore, we prospectively enrolled elderly patients with coronary heart disease (CHD) with diabetes mellitus (DM) undergoing elective drug-eluting stent (DES) implantation. They were randomized to receive RIPC within 2 hours before PCI (n = 102) or not (controls, n = 98). Baseline clinical characteristics were similar between the 2 groups. Despite a trend toward decline, the median high-sensitivity cardiac troponin I (hscTnI) level (P = .256) and the incidence of myocardial infarction (MI) type 4a (P = .106) in the RIPC group 16 hours after PCI procedure was not significantly different from the control group. The RIPC could attenuate the release of a myocardial biomarker but failed to show a significant effect on hscTnI level or MI type 4a incidence after PCI procedure in elderly patients with CHD having DM undergoing elective DES implantation.

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中科院(CAS)分区：

出版当年[2013]版：

大类 | 4 区医学

小类 | 4 区外周血管病

最新[2025]版：

大类 | 3 区医学

小类 | 3 区外周血管病

JCR分区：

出版当年[2012]版：

Q3 PERIPHERAL VASCULAR DISEASE

最新[2024]版：

Q3 PERIPHERAL VASCULAR DISEASE

影响因子： 2.2 最新[2024版] 2.6 最新五年平均 1.647 出版当年[2012版] 1.233 出版当年五年平均 1.511 出版前一年[2011版] 2.37 出版后一年[2013版]

第一作者：

第一作者机构： [1]Capital Med Univ, Beijing Inst Heart Lung & Blood Vessel Dis, An Zhen Hosp, Dept Cardiol, Beijing 100029, Peoples R China;

通讯作者：

通讯机构： [1]Capital Med Univ, Beijing Inst Heart Lung & Blood Vessel Dis, An Zhen Hosp, Dept Cardiol, Beijing 100029, Peoples R China; [3]Capital Med Univ, Beijing Inst Heart Lung & Blood Vessel Dis, An Zhen Hosp, Dept Cardiol, Anzhenli Ave, Beijing 100029, Peoples R China

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