研究单位：[1]Eli Lilly and Company[2]Isis Clinical Research Center,Guaynabo 4565119,Puerto Rico,00968[3]Novak Clinical Research - Tucson - North La Cholla Boulevard,Tucson 5318313,Arizona 5551752,United States,85741[4]Norcal Endocrinology & Internal Medicine,San Ramon 5392593,California 5332921,United States,94583[5]Southern California Clinical Research,Santa Ana 5392900,California 5332921,United States,92701[6]Care Access - Thousand Oaks,Thousand Oaks 5402405,California 5332921,United States,91360[7]Accel Research Sites - DeLand Clinical Research Unit,DeLand 4152890,Florida 4155751,United States,32720[8]Innovation Medical Research Center - Fort Lauderdale,Fort Lauderdale 4155966,Florida 4155751,United States,33316[9]Encore Medical Research,Hollywood 4158928,Florida 4155751,United States,33024[10]West Orange Endocrinology P.A.,Ocoee 4166776,Florida 4155751,United States,34761[11]Care Access - Tampa,Tampa 4174757,Florida 4155751,United States,33625[12]Accel Research Sites - NeuroStudies Clinical Research Unit,Decatur 4191124,Georgia 4197000,United States,30030[13]Care Access - Decatur,Decatur 4191124,Georgia 4197000,United States,30030[14]Javara - Privia Medical Group Georgia - Savannah,Savannah 4221552,Georgia 4197000,United States,31406[15]North Georgia Clinical Research,Woodstock 4231874,Georgia 4197000,United States,30189[16]Solaris Clinical Research,Meridian 5600685,Idaho 5596512,United States,83646[17]Care Access - New Iberia,New Iberia 4334971,Louisiana 4331987,United States,70560[18]Endocrine and Metabolic Consultants,Rockville 4367175,Maryland 4361885,United States,20852[19]Javara - Privia Medical Group - Silver Spring,Silver Spring 4369596,Maryland 4361885,United States,20901[20]Boeson Research MSO,Missoula 5666639,Montana 5667009,United States,59804[21]Javara - Nevada Health Centers - Carson City,Carson City 5501344,Nevada 5509151,United States,89706[22]The Machuca Foundation,Las Vegas 5506956,Nevada 5509151,United States,89101[23]University of North Carolina Medical Center,Chapel Hill 4460162,North Carolina 4482348,United States,27514[24]Javara - Tryon Medical Partners,Charlotte 4460243,North Carolina 4482348,United States,28210[25]Care Access - Fayetteville,Fayetteville 4466033,North Carolina 4482348,United States,28314[26]The Corvallis Clinic, P.C.,Corvallis 5720727,Oregon 5744337,United States,97330[27]Clinical Research of Philadelphia,Philadelphia 4560349,Pennsylvania 6254927,United States,19114[28]Frontier Clinical Research, LLC,Smithfield 4561301,Pennsylvania 6254927,United States,15478[29]Velocity Clinical Research, Dallas,Dallas 4684888,Texas 4736286,United States,75230[30]Biopharma Informatic, LLC,Houston 4699066,Texas 4736286,United States,77043[31]Texas Valley Clinical Research (TVCR) - Mission,Mission 4711725,Texas 4736286,United States,78572[32]Consano Clinical Research, LLC,Shavano Park 4728147,Texas 4736286,United States,78231[33]CARE - Centro de Alergia y Enfermedades Respiratorias,Ciudad Autónoma de Buenos Aires,Buenos Aires 3435907,Argentina,1414[34]CIPREC,Buenos Aires 3435910,Buenos Aires F.D. 3433955,Argentina,C1119ACN[35]Centro Médico Viamonte,Buenos Aires 3435910,Buenos Aires F.D. 3433955,Argentina,C1120AAC[36]Instituto Centenario,CABA,Buenos Aires F.D. 3433955,Argentina,1204[37]Instituto Médico Catamarca IMEC,Rosario 3838583,Santa Fe Province 3836276,Argentina,2000[38]Centro de Diagnóstico y Rehabilitación (CEDIR),Santa Fe 3836277,Argentina,3000[39]The Second People''s Hospital of Hefei,Hefei 1808722,Anhui 1818058,China,230011[40]Xuanwu Hospital Capital Medical University,Beijing 1816670,Beijing Municipality 2038349,China,100053[41]Peking University Third Hospital,Beijing 1816670,Beijing Municipality 2038349,China,100091[42]The Second Affiliated Hospital Chongqing Medical University,Chongqing 1814906,Chongqing Municipality 1814905,China,400010[43]Zhujiang Hospital,Guangzhou 1809858,Guangdong 1809935,China,510280[44]The Fourth Affiliated Hospital of Harbin Medical University,Harbin 2037013,Heilongjiang 2036965,China,150001[45]The First Affiliated Hospital of Henan University of Science &Technology,Luoyang Shi,Henan 1808520,China,471003[46]Zhongda Hospital Southeast University,Nanjing 1799962,Jiangsu 1806260,China,210009[47]The Second Affiliated Hospital of Nanjing Medical University,Nanjing 1799962,Jiangsu 1806260,China,210011[48]Jinan Central Hospital,Jinan 1805753,Shandong 1796328,China,250013[49]Sichuan Provincial People''s Hospital,Chengdu 1815286,Sichuan 1794299,China,610072[50]The Second Hospital of Tianjin Medical University,Tianjin 1792947,Tianjin Municipality 1792943,China,300211[51]MUDr. Alena Vachova,České Budějovice 3077916,Jihočeský kraj 3339537,Czechia,37011[52]VASOMED Clinic,Ostrava 3068799,Moravskoslezský kraj 3339573,Czechia,710 00[53]Milan Kvapil s.r.o., Diabetologicka ambulance,Prague 3067696,Praha 4,Czechia,14900[54]Medical Plus,Uherské Hradiště 3063739,Zlín 3339578,Czechia,686 01[55]Nemocnice Cesky Krumlov,Český Krumlov 3077889,Czechia,381 01[56]Medicover Neuroendokrinologie,Munich 2867714,Bavaria 2951839,Germany,81667[57]InnoDiab Forschung Gmbh,Essen 2928810,North Rhine-Westphalia 2861876,Germany,45136[58]Medizentrum Essen Borbeck,Essen 2928810,North Rhine-Westphalia 2861876,Germany,45355[59]AmBeNet GmbH,Leipzig 2879139,Saxony 2842566,Germany,04107[60]Gemeinschaftspraxis Dr. Taeschner/Dr. Bonigut,Leipzig 2879139,Saxony 2842566,Germany,04249[61]RED-Institut GmbH,Oldenburg in Holstein 2857451,Schleswig-Holstein 2838632,Germany,23758[62]Diabetes Zentrum Wilhelmsburg,Hamburg 2911298,Germany,21109[63]Apollo Excelcare Hospital,Guwahati 1271476,Assam 1278253,India,781033[64]Karnataka Institute of Medical Sciences,Hubli 10439747,Karnataka 1267701,India,580021[65]Chellaram Diabetes Institute,Pune 1259229,Maharashtra 1264418,India,411021[66]Sir Ganga Ram Hospital,New Delhi 1261481,National Capital Territory of Delhi 1273293,India,110060[67]All India Institute of Medical Sciences,Bhubaneswar 1275817,Odisha 1261029,India,751019[68]Diabetes Research Center,Hyderabad 1269843,Telangana 1254788,India,500082[69]All India Institute of Medical Sciences - Rishikesh,Rishikesh 1258128,Uttarakhand 1444366,India,249203[70]Tokuyama Clinic,Mihama-ku,Chiba City 2113015,Chiba 2113014,Japan,261-0004[71]Hasegawa Medical Clinic,Chitose 2130452,Hokkaido 2130037,Japan,066-0032[72]Tsuchiura Medical & Health Care Center,Tsuchiura 6822099,Ibaraki 2112669,Japan,300-0012[73]Noritake Clinic,Ushiku 2110629,Ibaraki 2112669,Japan,300-1207[74]Olive Takamatsu Medical Clinic,Takamatsu 1851100,Kagawa-ken 1860834,Japan,760-0076[75]Medical Corporation Yuga Tsuruma Kaneshiro Diabetes Clinic,Yamato-shi,Kanagawa 1860291,Japan,242-0004[76]Yokohama Minoru Clinic,Yokohama 1848354,Kanagawa 1860291,Japan,232-0064[77]Medical Corporation Heishinkai OCROM Clinic,Suita-shi,Osaka 1853904,Japan,565-0853[78]The Institute of Medical Science, Asahi Life Foundation,Chuo-ku,Tokyo 1850144,Japan,103-0002[79]Tokyo-Eki Center-building Clinic,Chuo-ku,Tokyo 1850144,Japan,103-0027[80]Fukuwa Clinic,Chuo-ku,Tokyo 1850144,Japan,104-0031[81]Medical Corporation Heishinkai ToCROM Clinic,Shinjuku-ku,Tokyo 1850144,Japan,160-0008[82]Shimokitazawa Tomo Clinic,Tokyo 1850147,Japan,155-0031[83]Diseno y Planeacion en Investigacion Medica - Guadalajara - Calle Amado Nervo,Guadalajara 4005539,Jalisco 4004156,Mexico,44600[84]RM Pharma Specialists - Unidad Especializada en Datos,Mexico City 3530597,Mexico City 3527646,Mexico,03100[85]Endocrinologia Especializada,Mexico City 3530597,Mexico City 3527646,Mexico,11700[86]Centro Medico Zambrano Hellion,San Pedro Garza García 4005937,Nuevo León 3522542,Mexico,66278[87]Kohler & Milstein Research S.A. De C.V.,Mérida 3523349,Yucatán 3514211,Mexico,97070[88]Medical Care and Research SA de CV,Mérida 3523349,Yucatán 3514211,Mexico,97070[89]Enclifar Ensayos Clínicos Farmacológicos Sc,Chihuahua City 4014338,Mexico,31110[90]Puerto Rico Health and Wellness Institute,Dorado 4564133,Puerto Rico,00646
研究目的：
The purpose of this Master Protocol is to support two studies to see how well and how safely orforglipron works compared to placebo in participants who have obesity or overweight with or without type 2 diabetes. Participants will be screened for about 4 weeks, after which they will enroll into either J2A-MC-GZP1, NCT06972459 (do not have type 2 diabetes) or J2A-MC-GZP2, NCT06972472 (have type 2 diabetes).
