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Investigating the Role of Zinc in Atherosclerosis: A Review

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收录情况： ◇ SCIE

作者：

机构： [1]Department of Neurology, Institute of Cerebrovascular Diseases Research, Xuanwu Hospital of Capital Medical University, No. 45 Changchun Street, Beijing 100053, China. [2]Peking Union Medical College, No. 9 Dongdansantiao Street, Beijing 100730, China. [3]Beijing Institute for Brain Disorders, No. 10 Xitoutiao, You An Men, Beijing 100069, China. [4]Department of Neurosurgery, China International Neuroscience Institute, Xuanwu Hospital of Capital Medical University, National Center for Neurological Disorders, No. 45 Changchun Street, Beijing 100053, China.

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关键词： zinc atherosclerosis zinc homeostasis-associated proteins endothelial cells vascular smooth muscle cell immune cell cardiovascular risk factors animal study human study

摘要：

Zinc, an indispensable micronutrient for human health, might play an important role in the development of atherosclerosis. Zinc could be involved in the atherogenic process through interaction with atherogenic cells, such as endothelial cells (ECs), vascular smooth muscle cells (VSMCs), and immune cells. In addition, zinc also exerts important positive or negative functions in various atherosclerosis-related risk factors, including lipid metabolism, glucose metabolism, and blood pressure. Currently, evidence focusing on the relationship between zinc status and atherogenic risk factors has been well established, while the direct interaction between zinc and atherosclerosis has not been fully understood. In this review, we aimed to summarize the association between zinc and atherosclerosis and explore current findings on how zinc and zinc homeostasis-associated proteins act in the atherogenic processes.

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出版当年[2021]版：

大类 | 3 区生物学

小类 | 3 区生化与分子生物学

最新[2025]版：

大类 | 2 区生物学

小类 | 3 区生化与分子生物学

JCR分区：

出版当年[2020]版：

Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY

最新[2023]版：

Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

影响因子： 4.8 最新[2023版] 5.4 最新五年平均 4.879 出版当年[2020版] 5.362 出版当年五年平均 4.082 出版前一年[2019版] 6.064 出版后一年[2021版]

第一作者：

第一作者机构： [1]Department of Neurology, Institute of Cerebrovascular Diseases Research, Xuanwu Hospital of Capital Medical University, No. 45 Changchun Street, Beijing 100053, China.

共同第一作者：

通讯作者：

通讯机构： [1]Department of Neurology, Institute of Cerebrovascular Diseases Research, Xuanwu Hospital of Capital Medical University, No. 45 Changchun Street, Beijing 100053, China. [3]Beijing Institute for Brain Disorders, No. 10 Xitoutiao, You An Men, Beijing 100069, China.

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Investigating the Role of Zinc in Atherosclerosis: A Review

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