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Percutaneous revascularization for atherosclerotic renal artery stenosis: a meta-analysis

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机构: [1]Department of General Surgery,Xuanwu Hospital, Capital Medical University, Beijing, China [2]Department of Vascular Surgery, Xuanwu Hospital, Capital Medical University, Beijing, China
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关键词: Atherosclerotic renal artery stenosis (ARAS) Meta-analysis Percutaneous revascularization (PR) Medicatio therapy alone

摘要:
This study investigates whether medication therapy alone is as effective and safe as percutaneous revascularization (PR) in patients with atherosclerotic renal artery stenosis (ARAS).The Embase, PubMed, and Cochrane Library databases were searched from their inception to July 31, 2021, for randomized controlled trials (RCTs) reporting PR for ARAS. RevMan 5.3 was employed to analyze the retrieved articles.Eight studies with a total of 2,225 ARAS patients were included in this analysis, demonstrating that PR and medication therapy alone had a similar effect on both systolic [mean difference (MD)= 0.19, 95% CI: -1.64- 2.02] and diastolic blood pressure (MD= -0.44, 95% CI: -1.68-0.80). Meanwhile, there were no differences in all-cause mortality [Odds ratio (OR) = 0.89, 95% CI: 0.70-1.14], stroke (OR = 0.84, 95% CI: 0.55-1.31), congestive heart failure (OR = 0.89, 95% CI: 0.67-1.19), and perioperative complications (OR = 0.87, 95% CI: 0.68-1.12).Medication therapy alone is as effective and safe as PR.

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大类 | 4 区 医学
小类 | 4 区 药学
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Q2 PHARMACOLOGY & PHARMACY
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第一作者机构: [1]Department of General Surgery,Xuanwu Hospital, Capital Medical University, Beijing, China
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