详情页 - 首都医科大学宣武医院知识库

当前位置：首页 > 详情页

Hemodynamic indicators of the formation of tandem intracranial aneurysm based on a vascular restoration algorithm

63| 导出 | 链接全文 |

文献详情

资源类型：

WOS体系：

Pubmed体系：

收录情况： ◇ SCIE

作者：

机构： [1]School of Life Science, Beijing Institute of Technology, Beijing, China. [2]Department of Interventional Neuroradiology, Beijing Neurosurgical Institute and Beijing Tiantan Hospital, Capital Medical University, Beijing, China. [3]School of Medical Imaging, North Sichuan Medical College, Nanchong, China. [4]Department of Radiology and Nuclear Medicine, Xuanwu Hospital, Capital Medical University, Beijing, China. [5]Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics, Beijing, China. [6]School of Medical Technology, Beijing Institute of Technology, Beijing, China.

出处：

DOI：

ISSN：

关键词： tandem intracranial aneurysms hemodynamics vortex core growth sequence vascular restoration algorithm

摘要：

Hemodynamic factors are believed to be closely related to IA growth. However, the underlying pathophysiological mechanism that induces the growth sequence in tandem intracranial aneurysms (IAs) remains unclear.This study involved five patients with tandem IAs. Aneurysm models were reconstructed based on image datasets. A novel vascular restoration algorithm was proposed to generate the hypothetical geometry of the healthy parent vessel before each IA formation in the concatenated structure. Detailed hemodynamic patterns and morphological features were revealed under various growth sequences of tandem IAs to investigate the flow-driven mechanism of IA growth. Potential hemodynamic indicators of IA formation were proposed.The patient cases were divided into two groups based on the size difference of tandem IAs. In the group with a similar size of tandem IAs, the position of the vortex core was associated with the site of the secondary aneurysm, while in the group with a significant size difference of the IAs, the position with the maximum curvature of the parent vessel plays a significant role in aneurysm formation.This study preliminarily revealed key hemodynamic and morphological indicators that determine the formation of tandem IAs. The proposed vascular restoration algorithm that provided the pre-aneurysm vasculature might be useful in investigating the flow-driven mechanism of IA growth, thus contributing to the risk evaluation of secondary aneurysm formation.Copyright © 2022 Yao, Tong, Mei, Yu, Shan, Liu and Chen.

基金：

语种：

被引次数：

WOS：

PubmedID：

中科院(CAS)分区：

出版当年[2021]版：

大类 | 3 区医学

小类 | 3 区临床神经病学 3 区神经科学

最新[2025]版：

大类 | 3 区医学

小类 | 3 区临床神经病学 3 区神经科学

JCR分区：

出版当年[2020]版：

Q2 NEUROSCIENCES Q2 CLINICAL NEUROLOGY

最新[2023]版：

Q2 CLINICAL NEUROLOGY Q3 NEUROSCIENCES

影响因子： 2.7 最新[2023版] 3.3 最新五年平均 4.003 出版当年[2020版] 4.189 出版当年五年平均 2.889 出版前一年[2019版] 4.086 出版后一年[2021版]

第一作者：

第一作者机构： [1]School of Life Science, Beijing Institute of Technology, Beijing, China.

共同第一作者：

通讯作者：

通讯机构： [1]School of Life Science, Beijing Institute of Technology, Beijing, China. [6]School of Medical Technology, Beijing Institute of Technology, Beijing, China.

推荐引用方式(GB/T 7714)：

APA：

MLA：

Hemodynamic indicators of the formation of tandem intracranial aneurysm based on a vascular restoration algorithm

文献详情

相关文献