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Temporal trend and attributable risk factors of Alzheimer's disease and other dementias burden in China: Findings from the Global Burden of Disease Study 2021

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WOS体系：
Pubmed体系：

收录情况： ◇ SCIE

作者：
Yang Kun[1] * ; Yang Xuan[2,3] ; Yin Peng[3] ; Zhou Maigeng[2,3] ; Tang Yi[4] ;
机构： [1]National Center for Neurological Disorders, Xuanwu Hospital, Capital Medical University, Beijing, P.R. China [2]Department of Epidemiology, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, P.R. China [3]National Centre for Chronic and Noncommunicable Disease Control and Prevention, Chinese Centre for Disease Control and Prevention, Beijing, P.R. China [4]Department of Neurology & Innovation Center for Neurological Disorders, Xuanwu Hospital, Capital Medical University, National Center for Neurological Disorders, Beijing, P.R. China
出处：
DOI： 10.1002/alz.14254
ISSN：

关键词： Alzheimer’s disease and other dementias disability-adjusted life years Global Burden of Diseases Study incidence mortality prevalence

摘要：
We examined the burden of Alzheimer's disease and other dementias (ADOD) and attributable factors at the national and provincial levels in China.Using the Global Burden of Diseases Study 2021, we estimated incidence, prevalence, mortality rate, disability-adjusted life years (DALYs), and the ratio of years lived with disability (YLD) to DALYs for ADOD in China. Estimated annual percentage changes (EAPCs) were used to quantify the temporal trends from 1990 to 2021.In 2021, China experienced the highest ADOD burden among Group of 20 member nations. The EAPCs for age-standardized rates for incidence, age-standardized rates for prevalence, and age-standardized mortality rate were 0.41 (uncertainty intervals [UIs] 0.34-0.49); 0.44 (UI: 0.36-0.52); and -0.19 (UI: -0.23 to -0.15), respectively. Between 1990 and 2021, the number of people with ADOD increased by 322.18% and DALYs associated with ADOD increased by 272.71%; most of these increases were explained by population aging.Considering the aging Chinese population, targeted strategies to prevent dementia are urgently needed.China experienced the highest dementia burden among Group of 20 member nations. High body mass index, high fasting plasma glucose, and smoking were major risk factors for Alzheimer's disease and other dementias (ADOD) burden. Since 1990, the incidence and prevalence of ADOD increased substantially in China. The mortality rate related to ADOD decreased consistently. Considering the aging Chinese population, targeted strategies are urgently needed.© 2024 The Author(s). Alzheimer's & Dementia published by Wiley Periodicals LLC on behalf of Alzheimer's Association.

基金：
National Key R&D Program of China (2022YFC3602600), the National Natural Science Foundation of China (82220108009, 81970996), and STI2030-Major Projects (2021ZD0201801).
语种：
外文
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2023]版：
大类 | 1 区 医学
小类 | 1 区 临床神经病学
最新[2023]版：
大类 | 1 区 医学
小类 | 1 区 临床神经病学
JCR分区：
出版当年[2022]版：
Q1 CLINICAL NEUROLOGY
最新[2023]版：
Q1 CLINICAL NEUROLOGY

影响因子： 最新[2023版] 最新五年平均 出版当年[2022版] 出版当年五年平均 出版前一年[2021版] 出版后一年[2023版]

第一作者：
第一作者机构： [1]National Center for Neurological Disorders, Xuanwu Hospital, Capital Medical University, Beijing, P.R. China
通讯作者：
通讯机构： [2]Department of Epidemiology, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, P.R. China [3]National Centre for Chronic and Noncommunicable Disease Control and Prevention, Chinese Centre for Disease Control and Prevention, Beijing, P.R. China
推荐引用方式(GB/T 7714)：
Yang Kun,Yang Xuan,Yin Peng,et al.Temporal trend and attributable risk factors of Alzheimer's disease and other dementias burden in China: Findings from the Global Burden of Disease Study 2021[J].Alzheimer's & Dementia : The Journal Of The Alzheimer's Association.2024,20(11):7871-7884.doi:10.1002/alz.14254.
APA：
Yang Kun,Yang Xuan,Yin Peng,Zhou Maigeng&Tang Yi.(2024).Temporal trend and attributable risk factors of Alzheimer's disease and other dementias burden in China: Findings from the Global Burden of Disease Study 2021.Alzheimer's & Dementia : The Journal Of The Alzheimer's Association,20,(11)
MLA：
Yang Kun,et al."Temporal trend and attributable risk factors of Alzheimer's disease and other dementias burden in China: Findings from the Global Burden of Disease Study 2021".Alzheimer's & Dementia : The Journal Of The Alzheimer's Association 20..11(2024):7871-7884

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