机构：[1]Neurology, Kailuan General Hospital, North China University of Science and Technology, Tangshan, China[2]Key Laboratory of Neurobiological Function in Hebei Province, Tangshan, China[3]Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, China神经科系统神经外科首都医科大学宣武医院
Objective: Face recognition is an important cognitive function of the human brain. Post stroke depression (PSD) is a common mental complication after stroke, which has a serious impact on individual physical function recovery and quality of life. This study aims to explore the face perception characteristics of PSD through electrophysiological indicators N170 and VPP, and provide an objective basis for the early evaluation of facial cognitive dysfunction in PSD. Methods: 58 patients in the cerebral small vessel disease (CSVD) with depressive symptoms (PSD) and 188 patients in the pure CSVD (NPSD). At the same time, 30 healthy subjects were selected as the healthy controls (HC). The differences of N170 and VPP components between the three groups were compared under the stimulation of inverted faces and upright faces. Results: PSD patients exhibited significantly longer peak latency and lower amplitude of N170 and VPP under both inverted and upright face stimulation compared to HC and NPSD. These results suggest that PSD patients have defects in early face recognition, there are abnormalities in the early perception and structural encoding of face information, and both the "overall mechanism" and "feature mechanism" of face recognition are damaged. Conclusions: These findings provide neuroelectrophysiological evidence for impaired emotionless face recognition in PSD patients.
基金：
The 2020 Hebei Province Innovation Capacity Improvement Plan Project [20567622H]; The 2022 Tangshan City Municipal Science and Technology Plan Project [22130212G]; The 2020 Hebei Province Medical Scientific Research Project Plan [20201283]
第一作者机构：[1]Neurology, Kailuan General Hospital, North China University of Science and Technology, Tangshan, China[2]Key Laboratory of Neurobiological Function in Hebei Province, Tangshan, China
共同第一作者：
通讯作者：
通讯机构：[1]Neurology, Kailuan General Hospital, North China University of Science and Technology, Tangshan, China[2]Key Laboratory of Neurobiological Function in Hebei Province, Tangshan, China
推荐引用方式(GB/T 7714)：
Zhang Pingshu,Cao Lingyun,Yuan Jianxin,et al.Early Impairment of Face Perception in Post-Stroke Depression: An ERP Study[J].CLINICAL EEG AND NEUROSCIENCE.2024,doi:10.1177/15500594241289473.
APA：
Zhang, Pingshu,Cao, Lingyun,Yuan, Jianxin,Wang, Changming,Ou, Ya...&Yuan, Xiaodong.(2024).Early Impairment of Face Perception in Post-Stroke Depression: An ERP Study.CLINICAL EEG AND NEUROSCIENCE,,
MLA：
Zhang, Pingshu,et al."Early Impairment of Face Perception in Post-Stroke Depression: An ERP Study".CLINICAL EEG AND NEUROSCIENCE .(2024)
