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北京市社区老年人群身体形态指数与全因死亡的关联研究

Association between a body shape index and all-cause mortality in the elderly in communities of Beijing

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收录情况: ◇ 统计源期刊 ◇ 北大核心 ◇ 卓越:领军期刊 ◇ 中华系列

机构: [1]解放军医学院,北京 100853 [2]中国人民解放军总医院第二医学中心老年医学研究所, 衰老及相关疾病研究北京市重点实验室,国家老年疾病临床医学研究中心,北京 100853 [3]首都医科大学附属北京友谊医院老年医学科,北京 100050 [4]中国人民解放军 总医院第二医学中心心血管内科,北京 100853 [5]中国人民解放军总医院研究生院三防 医学教研室,北京 100853 [6]首都医科大学宣武医院循证医学中心,北京 100053 [7]北京 密云区中医医院,北京 101500 [8]中国人民解放军总医院第一医学中心疾病预防控制 科,北京 100853 [9]肾脏疾病国家重点实验室,北京 100853
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关键词: 老年人  身体形态指数  全因死亡  队列研究

摘要:
Objective: To describe and analyze the distribution characteristics of a body shape index (ABSI) and its association with all-cause mortality in the elderly in communities of Beijing. Methods: The baseline and follow-up data of 10 423 subjects in Beijing Healthy Aging Cohort Study were used. The endpoint outcome was all-cause mortality in follow-up. The associations of ABSI, BMI and waist circumference with all-cause mortality were analyzed with a Cox proportional hazard regression model. Results: The mean follow-up time in this cohort was 6.36 years and the all-cause mortality was 15.27%. The restricted cubic spline results showed that ABSI showed a "U" association with all-cause mortality in the total population. After adjustment for confounding factors, compared with the normal ABSI group, the risk for all-cause mortality was higher in the low ABSI group (HR=1.69, 95%CI: 1.32-2.17) and high ABSI group (HR=1.75, 95%CI: 1.40-2.18). Compared with the normal BMI group, low BMI was associated with an increased risk for all-cause mortality (HR=1.70, 95%CI: 1.40-2.08). Compared with the normal waist circumference group, central obesity was associated with a decreased risk for all-cause mortality (HR=0.89, 95%CI: 0.80-0.99). The results of gender specific analysis on ABSI association with all-cause mortality were similar to that in total population, but the strength of association varied among different age groups. Cross-grouping results showed that older people with normal BMI and waist circumference and abnormal ABSI had an increased risk of all-cause mortality (HR=1.91, 95%CI: 1.22-2.99). Conclusions: In Beijing, ABSI is correlated with the risk for all-cause mortality in the elderly population, which is more sensitive and specific than the traditional indicators (BMI and waist circumference). They can be used as one of the physical measurement indicators for all-cause mortality risk prediction in the health risk assessment and management in the elderly.

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第一作者机构: [1]解放军医学院,北京 100853 [2]中国人民解放军总医院第二医学中心老年医学研究所, 衰老及相关疾病研究北京市重点实验室,国家老年疾病临床医学研究中心,北京 100853
通讯作者:
通讯机构: [2]中国人民解放军总医院第二医学中心老年医学研究所, 衰老及相关疾病研究北京市重点实验室,国家老年疾病临床医学研究中心,北京 100853 [9]肾脏疾病国家重点实验室,北京 100853
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