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Sodium channel blockers for the treatment of focal epilepsy: A Chinese expert consensus

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机构: [1]Department of Neurology, West China Hospital of Sichuan University, Chengdu, PR China, 610041 [2]Department of Neurology, Huashan Hospital of Fudan University, Shanghai, PR China, 200040 [3]Institute of Neuroscience and Department of Neurology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, PR China, 510260 [4]Department of Neurology, First Affiliated Hospital of Chongqing Medical University, Chongqing, PR China, 400016 [5]Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, PR China, 100053 [6]Department of Neurology, Xiangya Hospital of Central South University, Changsha, PR China, 410031 [7]Shanxi Xijing Institute of Epilepsy and Brain Disease, Xi’an, PR China, 710000 [8]Department of Neurology, The Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou, PR China, 310009 [9]Department of Neurology, Henan Provincial People’s Hospital, Zhengzhou, PR China, 450003 [10]Department of Functional Neurosurgery, Beijing Children’s Hospital, Capital Medical University, Beijing, PR China, 100045 [11]Department of Neurology, The First Bethune Hospital of Jilin University, Changchun, PR China, 130021 [12]Department of Neurology, Institute of Neuroscience, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, PR China, 510260 [13]Department of Neurology, Provincial Hospital Affiliated to Shandong First Medical University, Jinan, PR China, 250001 [14]Department of Neurology, Zhongshan Hospital, Fudan University, Shanghai, PR China, 200032 [15]Epilepsy Center, The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, PR China, 730030 [16]Department of Neurology, The First Medical Center of Chinese PLA General Hospital, Beijing, PR China, 100000 [17]Department of Neurology, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, PR China, 210029 [18]Epilepsy Surgery Ward, Department of Neurosurgery, Beijing Tiantan Hospital, Beijing, PR China, 100070 [19]Department of Functional Neurosurgery, Sanbo Brain Hospital, Capital Medical University, Beijing, PR China, 100080 [20]Neuromedical Center, The Seventh Affiliated Hospital of Sun Yet-sun University, Shenzhen, PR China, 518000 [21]Department of Neurology, National Children’s Medical Center, Children’s Hospital of Fudan University, Shanghai, PR China, 201102 [22]Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, PR China, 430030
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关键词: Consensus Delphi Sodium channel blockers Focal epilepsy Focal seizure

摘要:
To provide consensus-based recommendations for the use of sodium channel blockers (SCBs) in the management of focal epilepsy.A three-round modified Delphi procedure was conducted among a Delphi panel of 24 Chinese experts to build a consensus. A steering committee developed 9 statements related to SCBs for the treatment of focal epilepsy, and these statements were evaluated and voted upon by the expert panel.The expert panel achieved consensus on nine statements regarding the treatment recommendations for oxcarbazepine, lamotrigine, lacosamide, eslicarbazepine, topiramate, zonisamide and cenobamate in focal epilepsy patients and treatment adjustments for SCBs.This is a Chinese expert consensus on the use of SCBs in focal epilepsy developed using the modified Delphi method. These recommendations can help clinicians in their practice and guide future research.Copyright © 2025 The Authors. Published by Elsevier Ltd.. All rights reserved.

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出版当年[2025]版:
大类 | 3 区 医学
小类 | 3 区 临床神经病学 3 区 神经科学
最新[2025]版:
大类 | 3 区 医学
小类 | 3 区 临床神经病学 3 区 神经科学
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出版当年[2023]版:
Q2 CLINICAL NEUROLOGY Q3 NEUROSCIENCES
最新[2023]版:
Q2 CLINICAL NEUROLOGY Q3 NEUROSCIENCES

影响因子: 最新[2023版] 最新五年平均 出版当年[2023版] 出版当年五年平均 出版前一年[2022版]

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第一作者机构: [1]Department of Neurology, West China Hospital of Sichuan University, Chengdu, PR China, 610041
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