Blood Oxygenation Level-Dependent Functional Magnetic Resonance Imaging in Early Days: Correlation between Passive Activation and Motor Recovery After Unilateral Striatocapsular Cerebral Infarction
机构：[1]Department of Neurology, the Second Affiliated Hospital of Soochow University, Suzhou, China[2]Departments of Medical Imaging,the Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, China.[3]Departments of Neurology, the Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, China.
Objective: This study aimed to investigate the correlation between the functional magnetic resonance imaging (fMRI) pattern and the motor function recovery of an affected limb during the passive movement of the affected limb at an early stage of the striatocapsular infarction (SCI). Methods: A total of 17 patients with an acute stage of SCI and 3 healthy volunteers as controls were included in this study. fMRI scans of passive movement were performed on the affected limbs of stroke patients within 1 week of onset. Follow-ups were carried out for the motor functions of the affected limbs (before fMRI scan, 1 month, and 3 months after the scan). Results: The control group showed that the activation was mainly located in the contralateral sensorimotor cortex (SMC) and the bilateral supplementary motor area (SMA). The fMRI scan region of interest for stroke patients can be divided into 3 types: type I includes mainly the affected side, bilateral SMC, and SMA with activation; type II includes SMC on the affected side and SMA with activation; type III includes only SMC on the affected side or M1 with activation. The recovery of type I patients was better and faster, while the recovery of type II patients was better but slower, but recovery of type III patients was poorer and slower. Conclusions: Multiple cortical activation patterns were noted during the passive movement of the affected limbs at an early stage of SCI, and a correlation was found between the different activation patterns and the clinical prognosis of patients.
基金：
This research was supported by the Natural Science Foundation
of Jiangsu Province, China (No.BK2011451) and the Health and Family
Planning Committee of Jiangsu Province (No.Z201618).
第一作者机构：[1]Department of Neurology, the Second Affiliated Hospital of Soochow University, Suzhou, China[2]Departments of Medical Imaging,the Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, China.
共同第一作者：
通讯作者：
通讯机构：[*1]Department of Neurology, the Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215004, China
推荐引用方式(GB/T 7714)：
Long-Jiang Zhou ,Wei Wang ,Yi Zhao ,et al.Blood Oxygenation Level-Dependent Functional Magnetic Resonance Imaging in Early Days: Correlation between Passive Activation and Motor Recovery After Unilateral Striatocapsular Cerebral Infarction[J].JOURNAL OF STROKE & CEREBROVASCULAR DISEASES.2017,26(11):2652-2661.doi:10.1016/j.jstrokecerebrovasdis.2017.06.036.
APA：
Long-Jiang Zhou,,Wei Wang,,Yi Zhao,,Chun-Feng Liu,,Xin-Jiang Zhang,...&Hua-Dong Li,.(2017).Blood Oxygenation Level-Dependent Functional Magnetic Resonance Imaging in Early Days: Correlation between Passive Activation and Motor Recovery After Unilateral Striatocapsular Cerebral Infarction.JOURNAL OF STROKE & CEREBROVASCULAR DISEASES,26,(11)
MLA：
Long-Jiang Zhou,,et al."Blood Oxygenation Level-Dependent Functional Magnetic Resonance Imaging in Early Days: Correlation between Passive Activation and Motor Recovery After Unilateral Striatocapsular Cerebral Infarction".JOURNAL OF STROKE & CEREBROVASCULAR DISEASES 26..11(2017):2652-2661
