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Clinical Significance of REM Sleep Behavior Disorders and Other Non-motor Symptoms of Parkinsonism

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收录情况: ◇ SCIE ◇ 统计源期刊 ◇ CSCD-C

机构: [1]Department of Neurology and Sleep Center, The Second Affiliated Hospital of Soochow University, Suzhou 215004, China [2]Institute of Neuroscience, Soochow University, Suzhou 215123, China
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关键词: Parkinson's disease Rapid eye movement sleep behavior disorder Risk factors Parkinsonism

摘要:
Rapid eye movement sleep behavior disorder (RBD) is one of the most common non-motor symptoms of parkinsonism, and it may serve as a prodromal marker of neurodegenerative disease. The mechanism underlying RBD is unclear. Several prospective studies have reported that specific non-motor symptoms predict a conversion risk of developing a neurodegenerative disease, including olfactory dysfunction, abnormal color vision, autonomic dysfunction, excessive daytime sleepiness, depression, and cognitive impairment. Parkinson's disease (PD) with RBD exhibits clinical heterogeneity with respect to motor and non-motor symptoms compared with PD without RBD. In this review, we describe the main clinical and pathogenic features of RBD, focusing on its association with other non-motor symptoms of parkinsonism.

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出版当年[2016]版:
大类 | 3 区 医学
小类 | 4 区 神经科学
最新[2023]版:
大类 | 2 区 医学
小类 | 3 区 神经科学
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出版当年[2015]版:
Q3 NEUROSCIENCES
最新[2023]版:
Q1 NEUROSCIENCES

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第一作者机构: [1]Department of Neurology and Sleep Center, The Second Affiliated Hospital of Soochow University, Suzhou 215004, China
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通讯机构: [1]Department of Neurology and Sleep Center, The Second Affiliated Hospital of Soochow University, Suzhou 215004, China [2]Institute of Neuroscience, Soochow University, Suzhou 215123, China
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