当前位置: 首页 > 详情页

Chronic Remote Ischemic Conditioning May Mimic Regular Exercise: Perspective from Clinical Studies

文献详情

资源类型:
WOS体系:

收录情况: ◇ SCIE

机构: [1]Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China [2]Beijing Key Laboratory of Hypoxic Conditioning Translational Medicine, Xuanwu Hospital, Capital Medical University, Beijing, China [3]Beijing Municipal Geriatric Medical Research Center, Beijing, China [4]National Clinical Research Center for Geriatric Disorders, Beijing, China
出处:
ISSN:

关键词: chronic remote ischemic conditioning regular exercise organ protection

摘要:
Chronic remote ischemic conditioning (RIC), particularly long-term repeated RIC, has been applied in clinical trials with the expectation that it could play its protective roles for protracted periods. In sports medicine, chronic RIC has also been demonstrated to improve exercise performance, akin to improvements seen with regular exercise training. Therefore, chronic RIC may mimic regular exercise, and they may have similar underlying mechanisms. In this study, we explored the common underlying mechanisms of chronic RIC and physical exercise in protecting multiple organs and benefiting various populations, the advantages of chronic RIC, and the challenges for its popularization. Intriguingly, several underlying mechanisms of RIC and exercise have been shown to overlap. These include the production of many autacoids, enhanced ability for antioxidant activity, modulating immune and inflammatory responses. Therefore, it appears that chronic RIC, just like regular exercise, has beneficial effects in unhealthy, sub-healthy and healthy individuals. Compared with regular exercise, chronic RIC has several advantages, which may provide novel insights into the area of exercise and health. Chronic RIC may enrich the modes of exercise, and benefit individuals with severe diseases. Also, the disabled, and sub-healthy individuals are likely to benefit from chronic RIC either as an alternative to exercise or an adjunct to pharmacological or non-pharmacological therapy.

基金:
语种:
被引次数:
WOS:
PubmedID:
中科院(CAS)分区:
出版当年[2017]版
大类 | 2 区 医学
小类 | 2 区 老年医学
最新[2023]版:
大类 | 2 区 医学
小类 | 3 区 老年医学
JCR分区:
出版当年[2016]版:
Q1 GERIATRICS & GERONTOLOGY
最新[2023]版:
Q1 GERIATRICS & GERONTOLOGY

影响因子: 最新[2023版] 最新五年平均 出版当年[2016版] 出版当年五年平均 出版前一年[2015版] 出版后一年[2017版]

第一作者:
第一作者机构: [1]Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China [2]Beijing Key Laboratory of Hypoxic Conditioning Translational Medicine, Xuanwu Hospital, Capital Medical University, Beijing, China
共同第一作者:
通讯作者:
通讯机构: [*1]Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China, 100053
推荐引用方式(GB/T 7714):
APA:
MLA:

资源点击量:16409 今日访问量:0 总访问量:869 更新日期:2025-01-01 建议使用谷歌、火狐浏览器 常见问题

版权所有©2020 首都医科大学宣武医院 技术支持:重庆聚合科技有限公司 地址:北京市西城区长椿街45号宣武医院