机构：[1]Faculty ofMedicine, American University of BeirutMedical Center, Beirut, Lebanon[2]Faculty of Medicine, Saint George University of London, Nicosia, Cyprus[3]Department of Biochemistry and Molecular Genetics, American University of Beirut, Beirut, Lebanon[4]Institute of Hypoxia Medicine, Xuanwu Hospital, Capital Medical University, 100053 Beijing, China首都医科大学宣武医院[5]Xuanwu-Banyan Biomarker Research and Assay Center, 100053 Beijing, China[6]Department of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine,American University of Beirut, Beirut, Lebanon[7]Department of Neurosciences, University of Messina, Via Consolare Valeria, 98125 Messina, Italy[8]Department of Psychiatry, Center for Neuroproteomics and Biomarkers Research, University of Florida, 100 S Newell Drive Rm: L4-100, Gainesville, FL 32611, USA
Stroke is the second leading cause of death worldwide and a major cause of long-term severe disability representing a global health burden and one of the highly researched medical conditions. Nanostructured material synthesis and engineering have been recently developed and have been largely integrated into many fields including medicine. Recent studies have shown that nanoparticles might be a valuable tool in stroke. Different types, shapes, and sizes of nanoparticles have been used for molecular/biomarker profiling and imaging to help in early diagnosis and prevention of stroke and for drug/RNA delivery for improved treatment and neuroprotection. However, these promising applications have limitations, including cytotoxicity, which hindered their adoption into clinical use. Future research is warranted to fully develop and effectively and safely translate nanoparticles for stroke diagnosis and treatment into the clinic. This work will discuss the emerging role of nanotheragnostics in stroke diagnosis and treatment applications.
第一作者机构：[1]Faculty ofMedicine, American University of BeirutMedical Center, Beirut, Lebanon
共同第一作者：
通讯作者：
通讯机构：[3]Department of Biochemistry and Molecular Genetics, American University of Beirut, Beirut, Lebanon[8]Department of Psychiatry, Center for Neuroproteomics and Biomarkers Research, University of Florida, 100 S Newell Drive Rm: L4-100, Gainesville, FL 32611, USA
推荐引用方式(GB/T 7714)：
Tarek H. Mouhieddine,Muhieddine M. Itani,Amaly Nokkari,et al.Nanotheragnostic Applications for Ischemic and Hemorrhagic Strokes: Improved Delivery for a Better Prognosis[J].CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS.2015,15(1):doi:10.1007/s11910-014-0505-1.
APA：
Tarek H. Mouhieddine,Muhieddine M. Itani,Amaly Nokkari,Changhong Ren,Georges Daoud...&Firas H. Kobeissy.(2015).Nanotheragnostic Applications for Ischemic and Hemorrhagic Strokes: Improved Delivery for a Better Prognosis.CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS,15,(1)
MLA：
Tarek H. Mouhieddine,et al."Nanotheragnostic Applications for Ischemic and Hemorrhagic Strokes: Improved Delivery for a Better Prognosis".CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS 15..1(2015)
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