机构:[a]Department of Neurology, Xuan Wu Hospital, Capital Medical University, Beijing, People’s Republic of China神经内科首都医科大学宣武医院[b]Department of Computer Science, University of Otago, Dunedin, New Zealand[c]Department of Neurology, Fu Xing Hospital, Capital Medical University, Beijing, People’s Republic of China[d]Evidence-Based Medicine Center, Xuan Wu Hospital, Capital Medical University, Beijing, People’s Republic of China首都医科大学宣武医院[e]Department of Medicine and Therapeutics, Chinese University of Hong Kong, Hong Kong SAR, People’s Republic of China[f]McGill Center for Studies in Aging, McGill University, Montreal, Quebec, Canada[g]Department of Geriatrics, Guangzhou Brain Hospital, Affiliated Hospital of Guangzhou Medical College, Guangzhou, Guangdong Province, People’s Republic of China[h]Department of Neurology, Affiliated Hospital of Guiyang Medical College, Guiyang, Guizhou Province, People’s Republic of China[i]Department of Neurology, Third Affiliated Hospital of Henan University of Traditional Chinese Medicine, Zhengzhou, Henan Province, People’s Republic of China[j]Department of Neurology, First Hospital of Jilin University, Changchun, Jinlin Province, People’s Republic of China[k]Department of Neurology, Fourth Hospital of Jilin University, Changchun, Jinlin Province, People’s Republic of China[l]Department of Neurology, Beijing Geriatric Hospital, Beijing, People’s Republic of China[m]National Center for Chronic and Noncommunicable Disease Control and Prevention, Beijing, People’s Republic of China[n]Department of Neurology, Tongren Hospital, Capital Medical University, Beijing, People’s Republic of China
Background: Epidemiologic studies on mild cognitive impairment (MCI) are limited in China. Methods: Using a multistage cluster sampling design, a total of 10,276 community residents (6096 urban, 4180 rural) aged 65 years or older were evaluated and diagnosed with normal cognition, MCI, or dementia. MCI was further categorized by imaging into MCI caused by prodromal Alzheimer's disease (MCI-A), MCI resulting from cerebrovascular disease (MCI-CVD), MCI with vascular risk factors (MCI-VRF), and MCI caused by other diseases (MCI-O). Results: The prevalences of overall MCI, MCI-A, MCI-CVD, MCI-VRF, and MCI-O were 20.8% (95% confidence interval [CI] = 20.0-21.6%), 6.1% (95% CI = 5.7-6.6%), 3.8% (95% CI = 3.4-4.2%), 4.9% (95% CI = 4.5-5.4%), and 5.9% (95% CI = 5.5-6.4%) respectively. The rural population had a higher prevalence of overall MCI (23.4% vs 16.8%, P < .001). Conclusions: The prevalence of MCI in elderly Chinese is higher in rural than in urban areas. Vascular-related MCI (MCI-CVD and MCI-VRF) was most common. (C) 2014 The Alzheimer's Association. All rights reserved.
基金:
the National Key Technology R&D Program in the Eleventh Five-Year Plan Period (2006BAI02B01)
the Major Program of Science and Technology Plan of Beijing (D111107003111009)
the Medical Elite Foundation from the Peking Public Health Bureau(2011-3-089)
第一作者机构:[a]Department of Neurology, Xuan Wu Hospital, Capital Medical University, Beijing, People’s Republic of China
通讯作者:
通讯机构:[a]Department of Neurology, Xuan Wu Hospital, Capital Medical University, Beijing, People’s Republic of China
推荐引用方式(GB/T 7714):
Jianping Jia,Aihong Zhou,CuibaiWei,et al.The prevalence of mild cognitive impairment and its etiological subtypes in elderly Chinese[J].ALZHEIMERS & DEMENTIA.2014,10(4):439-447.doi:10.1016/j.jalz.2013.09.008.
APA:
Jianping Jia,Aihong Zhou,CuibaiWei,Xiangfei Jia,FenWang...&Xiumin Dong.(2014).The prevalence of mild cognitive impairment and its etiological subtypes in elderly Chinese.ALZHEIMERS & DEMENTIA,10,(4)
MLA:
Jianping Jia,et al."The prevalence of mild cognitive impairment and its etiological subtypes in elderly Chinese".ALZHEIMERS & DEMENTIA 10..4(2014):439-447