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Successful treatment of a woman with relapsing neuromyelitis optica by interferon beta

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收录情况： ◇ SCIE

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机构： [1]Department of Neurology, Peking Union Medical College Hospital, 1 Shuaifuyuan, Dongcheng District, 100730 Beijing, China [2]Department of Neurology, Xuan Wu Hospital, Capital Medical University, Beijing, China

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关键词： Neuromyelitis optica Beta-interferon AQP4-IgG Anti-MOG IgG

摘要：

Neuromyelitis optica (NMO) is an antibody-mediated disease with the target antigen being the water channel aquaporin-4 (AQP4). More than 90% of NMO patients have relapse. Optimal treatments to prevent recurrence have not been established. Previous reports suggest that interferon beta (IFNB) has not been effective in NMO. However, we present a case of NMO with positive anti-myelin oligodendrocyte glycoprotein (MOG)(27-38) IgG and anti-AQP4 IgG treated with IFNB-1a successfully. The effect of IFNB on NMO and the role of anti-MOG antibodies in NMO deserve further study.

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出版当年[2011]版：

大类 | 4 区医学

小类 | 4 区临床神经病学 4 区神经科学

最新[2023]版：

大类 | 4 区医学

小类 | 4 区临床神经病学 4 区神经科学

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出版当年[2010]版：

Q3 CLINICAL NEUROLOGY Q4 NEUROSCIENCES

最新[2023]版：

Q2 CLINICAL NEUROLOGY Q3 NEUROSCIENCES

影响因子： 2.7 最新[2023版] 2.7 最新五年平均 1.22 出版当年[2010版] 1.271 出版当年五年平均 1.12 出版前一年[2009版] 1.315 出版后一年[2011版]

第一作者：

第一作者机构： [1]Department of Neurology, Peking Union Medical College Hospital, 1 Shuaifuyuan, Dongcheng District, 100730 Beijing, China

通讯作者：

通讯机构： [1]Department of Neurology, Peking Union Medical College Hospital, 1 Shuaifuyuan, Dongcheng District, 100730 Beijing, China

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