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Incidence and survival of symptomatic lacunar infarction in a Beijing population: a 6-year prospective study

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机构: [a]Department of Evidence-based Medicine, Xuanwu Hospital, Capital Medical University, Beijing [b]Department of Geriatrics, Xuanwu Hospital, Capital Medical University, Beijing [c]Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing [d]Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing [e]Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Health Sciences Center, Beijing, China
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关键词: China incidence lacunar infarction risk factors survival

摘要:
Background and purpose: The incidence of ischaemic stroke has increased or remained high in China; however, little population-based evidence is available on the incidence and survival of lacunar infarction (LAC). We examined the incidence of LAC in a northern Chinese (Beijing) population and monitored survival. Methods: A prospective registry population-based study was conducted over a 6-year period in a general, unselected, and representative community in Beijing with approximately 100 000 long-term permanent residents. All first-ever stroke cases were registered. Results: A total of 1184 patients with ischaemic stroke were identified; 36.9% (437 cases) were classified as LAC. Age-standardized incidence rates of LAC ranged from 24.0 to 51.3/100 000 with an average rate of 35.3/100 000 during study period. The incidence of LAC increased with age before 70 years. The incidence of non-LAC increased with age. There were no significant differences in crude incidence of LAC between men and women (78.4/100 000 vs. 75.4/100 000). The incidence of non-LAC was significantly higher in men than in women (155/100 000 vs. 107/100 000, P < 0.001). The 28-day case fatality proportions were significantly lower in patients with LAC (0.5%) versus non-LAC (14.9%). One year after acute stroke onset, the survival rates between LAC and non-LAC were similar. Conclusion: LAC is a common stroke subtype in Northern China. Men or the elderly are more likely to have non-LAC. Long-term survival following LAC is similar to non-LAC patients.

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出版当年[2011]版:
大类 | 3 区 医学
小类 | 3 区 临床神经病学 3 区 神经科学
最新[2023]版:
大类 | 2 区 医学
小类 | 2 区 神经科学 3 区 临床神经病学
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出版当年[2010]版:
Q1 CLINICAL NEUROLOGY Q2 NEUROSCIENCES
最新[2023]版:
Q1 CLINICAL NEUROLOGY Q1 NEUROSCIENCES

影响因子: 最新[2023版] 最新五年平均 出版当年[2010版] 出版当年五年平均 出版前一年[2009版] 出版后一年[2011版]

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第一作者机构: [a]Department of Evidence-based Medicine, Xuanwu Hospital, Capital Medical University, Beijing
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通讯机构: [*1]Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Health Sciences Center, Beijing 100191, China
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