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A novel haemodynamic cerebral aneurysm model of rats with normal blood pressure

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机构： [a]Department of Neurosurgery, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, 301 Middle Yanchang Road, Shanghai, China [b]Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, 45 Changchun Avenue, Beijing 100053, China [c]Neuroscience and Neuroengineering Center, Med-X Research Institute, Shanghai Jiao Tong University, 1954 Huashan Road, Shanghai, China

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关键词： Cerebral aneurysm Rat blood pressure model Synchrotron radiation angiography (SRA)

摘要：

Cerebral aneurysms of traditional animal models are usually too small to be imaged in vivo. A novel rat model induced by ligation of the unilateral common carotid artery and contralateral pterygopalatine and external carotid arteries was investigatid. To evaluate the morphological changes of the cerebral arteries, synchrotron radiation angiography was utilised at 1 month, 2 months and 3 months after induction. Cerebral aneurysms and expansion of anterior cerebral arteries in these rats were identified when the animals were alive. This novel model is useful for cerebral aneurysm research. (C) 2011 Elsevier Ltd. All rights reserved.

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出版当年[2011]版：

大类 | 4 区医学

小类 | 4 区临床神经病学 4 区神经科学

最新[2023]版：

大类 | 4 区医学

小类 | 4 区临床神经病学 4 区神经科学

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出版当年[2010]版：

Q4 CLINICAL NEUROLOGY Q4 NEUROSCIENCES

最新[2023]版：

Q3 CLINICAL NEUROLOGY Q4 NEUROSCIENCES

影响因子： 1.9 最新[2023版] 1.9 最新五年平均 1.165 出版当年[2010版] 1.232 出版当年五年平均 1.17 出版前一年[2009版] 1.247 出版后一年[2011版]

第一作者：

第一作者机构： [a]Department of Neurosurgery, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, 301 Middle Yanchang Road, Shanghai, China [b]Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, 45 Changchun Avenue, Beijing 100053, China

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通讯作者：

通讯机构： [a]Department of Neurosurgery, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, 301 Middle Yanchang Road, Shanghai, China [b]Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, 45 Changchun Avenue, Beijing 100053, China

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