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Cerebral diffusion tensor imaging in tuberous sclerosis

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机构: [a]Department of Radiology, Xuanwu Hospital, Capital University of Medical Sciences, Beijing 100053, China [b]Beijing Institute of Functional Neurosurgery, Xuanwu Hospital, Capital University of Medical Sciences, China [c]Department of Neurology, Xuanwu Hospital, Capital University of Medical Sciences, China
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关键词: Tuberous sclerosis MRI Diffusion tensor imaging

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Purpose: The purpose of this study was to investigate the features of the apparent diffusion coefficient (ADC) and fractional anisotropy (FA) in cortical tubers and white-matter lesions in patients with tuberous sclerosis (TS) using diffusion tensor imaging (DTI). Materials and methods: Conventional magnetic resonance imaging (MRI) and DTI were performed in 14 patients with clinically established TS. Based on these DT images, ADC and FA maps were generated. The ADC values in 32 cortical tubers, and the ADC and FA values in 18 white-matter lesions were measured and compared with those of the corresponding contralateral regions. Results: Compared with the corresponding contralateral regions, cortical tubers of TS patients had significantly higher ADC values (P<0.001); white-matter lesions had significantly higher ADC values (P<0.001) and significantly lower FA values (P<0.001). Conclusion: DTI is a useful tool for demonstrating changes in cortical tubers and white-matter lesions resulting from TS. (C) 2008 Elsevier Ireland Ltd. All rights reserved.

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出版当年[2008]版:
大类 | 4 区 医学
小类 | 4 区 核医学
最新[2023]版:
大类 | 3 区 医学
小类 | 3 区 核医学
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出版当年[2007]版:
Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
最新[2023]版:
Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

影响因子: 最新[2023版] 最新五年平均 出版当年[2007版] 出版当年五年平均 出版前一年[2006版] 出版后一年[2008版]

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第一作者机构: [a]Department of Radiology, Xuanwu Hospital, Capital University of Medical Sciences, Beijing 100053, China
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通讯机构: [a]Department of Radiology, Xuanwu Hospital, Capital University of Medical Sciences, Beijing 100053, China
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