机构：[a]State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, China[b]Huaxi MR Research Center (HMRRC), Department of Radiology, West China Hospital of Sichuan University, China[c]Department of Radiology, The First Affiliated Hospital, School of Medicine, Zhejiang University, China[d]Department of Neurology, Xuanwu Hospital, Capital Medical University, Chin神经内科首都医科大学宣武医院
The current study combined structural magnetic resonance imaging (sMRI) and diffusion tensor MRI (DT-MRI) to investigate both gray matter density (GMD) and white matter integrity (WMI) in 18 pianists and 21 age-matched non-musicians. The pianists began their piano training at a mean age of 12. Voxel-based morphometry of the sMRI data showed that the pianists had higher GMD in the left primary sensorimotor cortex and right cerebellum. Voxel-based analysis of the DT-MRI data showed that pianists had higher fractional anisotropy (FA) (indicating higher WMI) in the right posterior limb of the internal capsule. The sMRI and DT-MRI results indicate that both the GMD and WMI of pianists may exhibit movement-related increases during adolescence or even early adulthood compared with non-musicians. (C) 2008 Elsevier Ireland Ltd. All rights reserved.
基金：
Natural Science Foundation of China (30470575, 30625024, 30728017, 30530290 and 30621130074),
an SRFDP grant fromSEM (GrantNo. 20060610073), the National Basic Research Program of China (973 Program No.: 2007CB512305/1), and the National High Technology Program of China (863 Program No.: 2007AA02Z430).
第一作者机构：[a]State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, China[d]Department of Neurology, Xuanwu Hospital, Capital Medical University, Chin
通讯作者：
通讯机构：[*]State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, No. 19, Xin Jie Kou Wai Da Jie, Beijing 100875, China
推荐引用方式(GB/T 7714)：
Ying Han,Hong Yang,Ya-Ting Lv,et al.Gray matter density and white matter integrity in pianists' brain: A combined structural and diffusion tensor MRI study[J].NEUROSCIENCE LETTERS.2009,459(1):44991.doi:10.1016/j.neulet.2008.07.056.
APA：
Ying Han,Hong Yang,Ya-Ting Lv,Chao-Zhe Zhu,Yong He...&Qi Dong.(2009).Gray matter density and white matter integrity in pianists' brain: A combined structural and diffusion tensor MRI study.NEUROSCIENCE LETTERS,459,(1)
MLA：
Ying Han,et al."Gray matter density and white matter integrity in pianists' brain: A combined structural and diffusion tensor MRI study".NEUROSCIENCE LETTERS 459..1(2009):44991
