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Polymorphisms of dopamine receptor and transporter genes and hallucinations in Parkinson's disease

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机构: [a]Institute of Genetics, School of Life Science, Fudan University, Shanghai 200433, PR China [b]Department of Neurology, Xuanwu Hospital, Capital University of Medical Sciences, Beijing 100053, PR China [c]Department of Neurology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, PR China
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关键词: Parkinson's disease dopamine receptor transporter gene polymorphism hallucination

摘要:
The authors conducted a case-control study of Parkinson's disease patients with and without visual hallucinations to investigate associations of the polymorphisms of the dopamine receptors D2 32806 C > T (Taq1A), D3 Ser(9)Gly and Msp1, D5 978T > C and dopamine transporter 3'-UTR 40 bp VNTR with visual hallucinations in Parkinson's disease. No significant differences were found between hallucinators and non-hallucinators in either the genotypic or allelic distributions. Our data suggest that the loci investigated here are not associated with the visual hallucinogenesis in Parkinson's disease. (C) 2003 Elsevier Ireland Ltd. All rights reserved.

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大类 | 4 区 医学
小类 | 4 区 神经科学
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Q2 NEUROSCIENCES
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Q3 NEUROSCIENCES

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第一作者机构: [a]Institute of Genetics, School of Life Science, Fudan University, Shanghai 200433, PR China [*]Department of Pharmacological Sciences, SUNY at Stony Brook, Stony Brook, NY 11794-8651, USA
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通讯机构: [*]Department of Pharmacological Sciences, SUNY at Stony Brook, Stony Brook, NY 11794-8651, USA
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