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起源于颞叶的过度运动发作的电-临床特征分析

The electroclinical characteristics of hypermotor seizures originating from the temporal lobe

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收录情况: ◇ 统计源期刊 ◇ 北大核心 ◇ CSCD-C ◇ 中华系列

机构: [1]首都医科大学宣武医院/北京功能神经外科研究所, 100053 [2]首都医科大学宣武医院神经内科, 100053
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关键词: Hypermotor seizure Epilepsy Temporal lobe Electroencephalography Neurosurgical procedures

摘要:
Objective To describe the characteristics of electroclinical manifestations in patients with hypermotor seizures (HMSs) originating from the temporal lobe.Methods The data of 12 patients who had HMSs of temporal origin and underwent surgical treatment from April 2001 to February 2015 in Beijing Institute of Functional Neurosurgery were retrospectively reviewed,including seizure histories,imaging reports,video-electroencephalogram (EEG) monitoring,operative records and pathological findings.Results Ten of the 12 patients were reported auras.The ictal behavior included marked agitation in 7 patients and mild agitation in 5 patients.All of the 12 patients with HMSs concomitantly appeared contralateral stiffness or dystonia of the upper limb or both limbs to a certain extent.Eight of the 12 patients underwent intracranial recording,in which 29 seizures were recorded in total.The time interval from temporal EEG origination to the beginning of hypermotor behavior was (22.8 ± 8.4) s.The time interval of ictal propagation from the temporal to frontal lobe was (16.0 ± 8.2) s,and that from the frontal lobe involving to the beginning of hypermotor behavior was (6.3 ± 6.1) s,with statistically significant difference (t =4.442,P =0.000).All of the 12 patients were followed for 6 to 72 months after the anterior temporal lobectomy,in which 10 cases remained seizure-free,and 2 were only relieved from HMSs.Conclusions Some HMSs can originate from the temporal lobe and the hypermotor behaviors maybe occur when the ictal neural network involves the frontal lobe.Therefore,surgical resection may lead to satisfied outcomes.

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第一作者机构: [1]首都医科大学宣武医院/北京功能神经外科研究所, 100053
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