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Ischemic stroke pathophysiology and cell therapy

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机构： [1]Institute of Hypoxia Medicine, Xuanwu Hospital, Capital Medical University, Chang Chun Road 45, Beijing 100053, China [2]China-America Joint Institute for Neuroscience, Xuanwu Hospital, Capital medical University, Chang Chun Road 45, Beijing 100053, China [3]Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China [4]Institute of Hypoxia Medicine, Xuanwu Hospital, Capital Medical University, Beijing, China [5]China-America Joint Institute for Neuroscience, Xuanwu Hospital, Capital Medical University, Beijing, China

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关键词： Ischemia Stroke Transplantation

摘要：

Current evidence shows great promise for stem cell transplantation as a new strategy for stroke. However, stem cell transplantation for stroke is still in its infancy, with many issues that need to be addressed in order to achieve the full potential of stem cell therapy for stroke. Among the major hurdles for successful clinical translation is determining the time window, stem cell type selection, delivery route, and underlying cellular and molecular mechanisms. In this chapter, we attempt to review the basic knowledge of pathophysiology and summarize the different stem cells for stroke treatment. © Springer Nature Singapore Pte Ltd. 2017.

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第一作者机构： [1]Institute of Hypoxia Medicine, Xuanwu Hospital, Capital Medical University, Chang Chun Road 45, Beijing 100053, China

通讯作者：

通讯机构： [3]Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China [4]Institute of Hypoxia Medicine, Xuanwu Hospital, Capital Medical University, Beijing, China [5]China-America Joint Institute for Neuroscience, Xuanwu Hospital, Capital Medical University, Beijing, China

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