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Progress in heparin-functionalized biomaterials

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机构: [1]Department of Vascular Surgery, XuanWu Hospital, Capital Medical University, Beijing 100053, People’s Republic of China [2]Chinese Academy of Science, Institute of High Energy Physics, Beijing 100049, People’s Republic of China [3]School of Life Science and Technology, Beijing Institute of Technology, Beijing 100081, People’s Republic of China
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关键词: Biomaterials Functionalization Growth factors Heparin

摘要:
The present article reviews the recent progress on heparin functionalization of biomaterials. Achievements in materials preparation based on physical adsorption coatings, covalent graft, and biomimetic microcarriers are included. All these heparin-containing materials have antithrombogenicity or can control the release of growth factors, which have been extensively investigated. However, the research in the near future will focus on construction of various systems to control the release of heparin affinitive growth factors. © Springer-Verlag Berlin Heidelberg 2014.

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第一作者机构: [1]Department of Vascular Surgery, XuanWu Hospital, Capital Medical University, Beijing 100053, People’s Republic of China
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通讯机构: [2]Chinese Academy of Science, Institute of High Energy Physics, Beijing 100049, People’s Republic of China
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