机构：[1]Department of Ophthalmology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China临床科室眼科首都医科大学附属安贞医院[2]Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China首都医科大学附属同仁医院[3]Beijing Ophthalmology and Visual Sciences Key Lab, Beijing, China首都医科大学附属同仁医院[4]Astronaut Research and Training Center of China, Beijing, China航天员中心
Objective: To investigate the effects of hypergravity on retinal structure in rat. Methods: Retinal structure and protein expression were examined by hematoxylin and eosin stain, immunohistochemistry and Western blot in the Sprague-Dawley® rats induced by hypergravity with short arm centrifuge (+10 Gz/3 min). Results: Retinal structure had no substantial change after hypergravity stimulation, but the expression levels of glial fibrillary acidic protein and ciliary neurotrophic factor were significantly increased by hypergravity stimulation. Conclusion: Hypergravity induced the expression levels of ciliary neurotrophic factor, which protect retinal structure against hypergravity stimulation with short time and high +Gz value in rat.
语种：
外文
中科院(CAS)分区：
出版当年[2016]版：
大类|4 区医学
小类|4 区肿瘤学4 区病理学
最新[2023]版：
无
第一作者：
第一作者机构：[1]Department of Ophthalmology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China[2]Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China[3]Beijing Ophthalmology and Visual Sciences Key Lab, Beijing, China
通讯作者：
通讯机构：[2]Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China[3]Beijing Ophthalmology and Visual Sciences Key Lab, Beijing, China[4]Astronaut Research and Training Center of China, Beijing, China[*1]Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital,Beijing Ophthalmology & Visual Sciences Key Lab, Beijing 100730, China.[*2]Astronaut Research and Training Center of China, Beijing 100094, China.
推荐引用方式(GB/T 7714)：
Jia Guo,Xiao Li,Yang Zhao,et al.Ciliary neurotrophic factor protects retinal structure against hypergravity stimulation with short time and high +Gz value in rat[J].2017,10(3):
APA：
Jia Guo,Xiao Li,Yang Zhao,Ping Wu,Xiaoping Chen&Siquan Zhu.(2017).Ciliary neurotrophic factor protects retinal structure against hypergravity stimulation with short time and high +Gz value in rat.,10,(3)
MLA：
Jia Guo,et al."Ciliary neurotrophic factor protects retinal structure against hypergravity stimulation with short time and high +Gz value in rat". 10..3(2017)
