机构：[1]Department of Neurosurgery, Beijing Tiantan Hospital affiliated to Capital Medical University, Beijing重点科室诊疗科室神经外科神经外科首都医科大学附属天坛医院[2]National Clinical Research Center for Neurological Diseases, Center of Brain Tumor, Beijing Institute for Brain Disorders and Beijing Key Laboratory of Brian Tumor, Beijing, China
BACKGROUND: Dysplastic gangliocytoma of the cerebellum, also called Lhermitte-Duclos disease (LDD), is known as a rare, benign brain tumor. Around 200 cases have been reported. CASE DESCRIPTION: Here we introduced a newly diagnosed adult case with intratumoral hemorrhage. Then we reviewed 18 cases diagnosed in our institute, including 12 adults and 6 children. CONCLUSIONS: Preoperative diagnosis based on magnetic resonance imaging is 50% in adults and 16.7% in pediatrics. Diagnostic tiger stripes are not always seen in pediatric cases. The prognosis of the disease is good if total resection can be achieved. Further examinations for PTEN mutation and other comorbidities are recommended.
基金：
pediatric and adult tumor group of the neurosurgery department of Beijing Tiantan Hospital; neuro-radiology department of Beijing Tiantan Hospital; neuropathology department of Beijing Tiantan Hospital; Organization Department of Beijing Municipal Committee [20150000214696223]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China [81471229]
第一作者机构：[1]Department of Neurosurgery, Beijing Tiantan Hospital affiliated to Capital Medical University, Beijing[2]National Clinical Research Center for Neurological Diseases, Center of Brain Tumor, Beijing Institute for Brain Disorders and Beijing Key Laboratory of Brian Tumor, Beijing, China
通讯作者：
通讯机构：[1]Department of Neurosurgery, Beijing Tiantan Hospital affiliated to Capital Medical University, Beijing[2]National Clinical Research Center for Neurological Diseases, Center of Brain Tumor, Beijing Institute for Brain Disorders and Beijing Key Laboratory of Brian Tumor, Beijing, China
推荐引用方式(GB/T 7714)：
Ma Jun,Jia Guijun,Chen Siyuan,et al.Clinical Perspective on Dysplastic Gangliocytoma of the Cerebellum (Lhermitte-Duclos Disease)[J].WORLD NEUROSURGERY.2019,122:16-23.doi:10.1016/j.wneu.2018.10.085.
APA：
Ma, Jun,Jia, Guijun,Chen, Siyuan&Jia, Wang.(2019).Clinical Perspective on Dysplastic Gangliocytoma of the Cerebellum (Lhermitte-Duclos Disease).WORLD NEUROSURGERY,122,
MLA：
Ma, Jun,et al."Clinical Perspective on Dysplastic Gangliocytoma of the Cerebellum (Lhermitte-Duclos Disease)".WORLD NEUROSURGERY 122.(2019):16-23
