机构:[1]National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing, China[2]University of Chinese Academy of Sciences, Beijing, China zhaoxiaomei14@mails.ucas.ac.cn[3]Beijing Neurosurgical Institute, Capital Medical University, Beijing, China研究所北京市神经外科研究所首都医科大学附属天坛医院[4]Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China重点科室诊疗科室神经外科神经外科首都医科大学附属天坛医院[5]Beijing Institute for Brain Disorders Brain Tumor Center, Beijing, China[6]China National Clinical Research Center for Neurological Diseases, Beijing, China[7]Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
The Magnetic Resonance Images (MRI) which can be used to segment brain tumors are 3D images. To make use of 3D information, a method that integrates the segmentation results of 3 2D Fully Convolutional Neural Networks (FCNNs), each of which is trained to segment brain tumor images from axial, coronal, and sagittal views respectively, is applied in this paper. Integrating multiple FCNN models by fusing their segmentation results rather than by fusing into one deep network makes sure that each FCNN model can still be tested by 2D slices, guaranteeing the testing efficiency. An averaging strategy is applied to do the fusing job. This method can be easily extended to integrate more FCNN models which are trained to segment brain tumor images from more views, without retraining the FCNN models that we already have. In addition, 3D Conditional Random Fields (CRFs) are applied to optimize our fused segmentation results. Experimental results show that, integrating the segmentation results of multiple 2D FCNNs obviously improves the segmentation accuracy, and 3D CRF greatly reduces false positives and improves the accuracy of tumor boundaries.
基金:
National High Technology Research and Development Program of ChinaNational High Technology Research and Development Program of China [2015AA020504]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China [61572499, 61421004]
语种:
外文
被引次数:
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第一作者:
第一作者机构:[1]National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing, China[2]University of Chinese Academy of Sciences, Beijing, China zhaoxiaomei14@mails.ucas.ac.cn
通讯作者:
通讯机构:[1]National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing, China[2]University of Chinese Academy of Sciences, Beijing, China zhaoxiaomei14@mails.ucas.ac.cn