机构：[1]Department of Otolaryngology–Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China其他中心耳鼻咽喉头颈外科中心首都医科大学附属同仁医院[2]Department of Otolaryngology–Head and Neck Surgery, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China首都医科大学附属天坛医院[3]Department of Radiology, Beijing Tongren Hospital, Capital Medical University, Beijing, China医技科室放射科首都医科大学附属同仁医院
Background: The Draf 3 procedure has been demonstrated to be effective in the treatment of refractory frontal sinus disease. A variety of clinical factors may contribute to the change of frontal neo-ostium (FNO) area after this procedure. Imaging plays a vital role in the evaluation and follow-up after surgery and provides useful prognostic information. Objectives: (1) To investigate the influence of local anatomic factors on FNO after a Draf 3 procedure by radiological measurements on imaging software and (2) to explore other predictive factors of FNO restenosis. Methods: Twenty-four patients with chronic rhinosinusitis who underwent a Draf 3 procedure and were followed up for more than 12 months (2012-2014) were enrolled in this study. Data on patient demographics, medical history, and computed tomography scans were collected. Anatomic dimensions were measured with OsiriX (R) (Pixmeo, Geneva, Switzerland). Stenotic ostium was defined as a loss of more than 50% of the original intraoperative area. Multivariate linear regression was used to assess independent factors linked to frontal neo-osteogenesis 1 year after the surgery. A receiver operating characteristic curve was built for the cutoff value of preoperative dimension to predict restenosis of FNO area. Results: A significant association was demonstrated between the minimum anteroposterior diameter (FOAP(MIN)) of the frontal ostium preoperatively and FNO area 1 year postoperatively. Multivariate linear regression showed that FOAP(MIN) of the frontal ostium preoperatively and the percentage of serum eosinophils (EOSs) correlated with the contour area of the FNO 1 year postoperatively. FOAP(MIN) <= 3.592 mm yielded a sensitivity of 95% and a specificity of 75% for the diagnosis of FNO restenosis. Conclusions: Both FOAP(MIN) and EOS are independent predictors of the contour area of the FNO 1 year postoperatively. Patients with a higher risk of developing frontal ostium restenosis can be identified preoperatively by measurements of the frontal sinus anatomic dimensions.
基金：
Key Project of Beijing Municipal Commission of EducationBeijing Municipal Commission of Education [KZ201410025029]; Beijing Municipal Administration of Hospitals' Ascent Plan [DFL20150202]; Priming Scientific Research Foundation for the Junior Research in Beijing Tongren Hospital, Capital Medical University [2015-YJJ-ZZL-013]
第一作者机构：[1]Department of Otolaryngology–Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China
通讯作者：
通讯机构：[1]Department of Otolaryngology–Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China[*1]Department of Otolaryngology-Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, No. 1 Dong Jiao Min Xiang, Dongcheng District, Beijing 100730, China.
推荐引用方式(GB/T 7714)：
Zhang Xiaoqing,Ye Ting,Huang Zhenxiao,et al.Clinical Predictors of Frontal Ostium Restenosis After Draf 3 Procedure for Refractory Chronic Rhinosinusitis[J].AMERICAN JOURNAL OF RHINOLOGY & ALLERGY.2018,32(4):287-293.doi:10.1177/1945892418773625.
APA：
Zhang, Xiaoqing,Ye, Ting,Huang, Zhenxiao,Huang, Qian,Xian, Junfang...&Zhou, Bing.(2018).Clinical Predictors of Frontal Ostium Restenosis After Draf 3 Procedure for Refractory Chronic Rhinosinusitis.AMERICAN JOURNAL OF RHINOLOGY & ALLERGY,32,(4)
MLA：
Zhang, Xiaoqing,et al."Clinical Predictors of Frontal Ostium Restenosis After Draf 3 Procedure for Refractory Chronic Rhinosinusitis".AMERICAN JOURNAL OF RHINOLOGY & ALLERGY 32..4(2018):287-293
