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A rare case report and literatures review on primary germinoma in cerebellar hemisphere

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机构: [1]Capital Med Univ, Beijing Tiantan Hosp, Dept Pediat Neurosurg, Beijing 100050, Peoples R China; [2]Capital Med Univ, Beijing Neurosurg Inst, Beijing 100050, Peoples R China
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关键词: Germinoma Cerebellum CT scan Chemotherapy Radiotherapy

摘要:
Primary intracranial germinoma is a rare intracranial lesion which accounts for approximately 0.5-2% of all intracranial tumors. Generally, primary intracranial germinoma occurs in the midline structures of the central nervous system of a pediatric patient. Only four cases of primary cerebellar germinomas with poor prognosis have been previously reported. The object of this paper is to introduce a case of germinoma originating from cerebellar hemisphere and to discuss its clinical features. This paper reported an 8-year-old boy who was diagnosed to have cerebella inflammatory granuloma during hospitalization and then discharged without any operation. However, the follow-up MRs revealed that the lesion became larger. Therefore, the boy was hospitalized again and underwent a gross total resection of lesion. According to pathological examination, the final diagnosis was confirmed as germinoma. Chemo- and radiotherapy were followed and so far, the patient showed good recovery without any recurrence and metastasis. Primary cerebellar germinoma has been rarely described in previous literatures. In this paper, a primary cerebellar germinoma was reported and its clinical features and treatments were discussed. The tumor's significant shrinkage by CT- scan was firstly reported and maybe this would provide a valuable hint for the diagnosis and treatment on the intracranial germinomas in children.

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出版当年[2016]版:
大类 | 4 区 医学
小类 | 4 区 临床神经病学 4 区 儿科 4 区 外科
最新[2023]版:
大类 | 4 区 医学
小类 | 4 区 临床神经病学 4 区 儿科 4 区 外科
JCR分区:
出版当年[2015]版:
Q3 SURGERY Q3 PEDIATRICS Q4 CLINICAL NEUROLOGY
最新[2023]版:
Q3 SURGERY Q3 PEDIATRICS Q4 CLINICAL NEUROLOGY

影响因子: 最新[2023版] 最新五年平均 出版当年[2015版] 出版当年五年平均 出版前一年[2014版] 出版后一年[2016版]

第一作者:
第一作者机构: [1]Capital Med Univ, Beijing Tiantan Hosp, Dept Pediat Neurosurg, Beijing 100050, Peoples R China;
通讯作者:
通讯机构: [1]Capital Med Univ, Beijing Tiantan Hosp, Dept Pediat Neurosurg, Beijing 100050, Peoples R China; [2]Capital Med Univ, Beijing Neurosurg Inst, Beijing 100050, Peoples R China
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