The current study aimed to determine genes that changed continuously throughout the postnatal developmental process of the rat visual cortex. Tissue samples were taken at postnatal day 0, day 10 (before eye opening), day 20 (before the critical period) and day 45 (end of development) and subjected to microarray and real-time RT-PCR analyses. A temporal pattern of expression was revealed for 24 genes that continuously increased (18 genes) or decreased (6 genes) as visual cortex development progressed and were common among all age groups. Our data provide a relevant set of genes whose expression levels correlate with visual cortex development and represent a novel group that may affect temporal-specific regulation. (c) 2009 Elsevier Ireland Ltd. All rights reserved.
基金：
NSFCNational Natural Science Foundation of China [30572002]; Department of Science & Technology of Guangdong Province [2004A30801001]
第一作者机构：[1]Sun Yat Sen Univ, Zhongshan Ophthalm Ctr, State Key Lab Ophthalmol, Guangzhou 510060, Guangdong, Peoples R China;[2]Capital Med Univ, Beijing TianTan Hosp, Dept Ophthalmol, Beijing 100050, Peoples R China;
通讯作者：
通讯机构：[1]Sun Yat Sen Univ, Zhongshan Ophthalm Ctr, State Key Lab Ophthalmol, Guangzhou 510060, Guangdong, Peoples R China;[4]Sun Yat Sen Univ, Zhongshan Ophthalm Ctr, State Key Lab Ophthalmol, 54 S Xianlie Rd, Guangzhou 510060, Guangdong, Peoples R China
推荐引用方式(GB/T 7714)：
Yang Liu,Pan Zhujuan,Zhou Lihua,et al.Continuously changed genes during postnatal periods in rat visual cortex[J].NEUROSCIENCE LETTERS.2009,462(2):162-165.doi:10.1016/j.neulet.2009.07.004.
APA：
Yang, Liu,Pan, Zhujuan,Zhou, Lihua,Lin, Shaochun&Wu, Kaili.(2009).Continuously changed genes during postnatal periods in rat visual cortex.NEUROSCIENCE LETTERS,462,(2)
MLA：
Yang, Liu,et al."Continuously changed genes during postnatal periods in rat visual cortex".NEUROSCIENCE LETTERS 462..2(2009):162-165
