Objective To introduce the features of germinomas arising from the basal ganglia (BG) and thalamus. Method Retrospective analysis was done with the clinical cases of germinomas in BG and thalamus from 1996 to 2000. The data included the symptoms, signs, neuroimaging findings, treatment, and outcomes. Result Fourteen cases were included, only one female was included. The main symptoms are disorder of numbness and weakness in limbs. Neuroimaging showed no or mild peritumor high signal in T2 weighted imaging of magnetic resonance, accompanied with cyst, calcification or bleeding. Total gross resection was obtained in nine cases, subtotal resection in four. Follow-up data were available in 11 cases with average of 56 months. Eight cases underwent only postoperative radiotherapy, one underwent only chemotherapy, and two underwent both. One case died of complication 6 months after chemotherapy, the rest lived good life. Conclusion Germinoma in BG and thalamus predominate in a boy. The neuroimaging features are very informative for diagnosis. Surgical resection should not be the first choice although it is has lesser complications. The long-term outcome is favorable.
第一作者机构：[1]Capital Univ Med Sci, Beijing Tiantan Hosp, Dept Neurosurg, Beijing 100050, Peoples R China;
通讯作者：
通讯机构：[1]Capital Univ Med Sci, Beijing Tiantan Hosp, Dept Neurosurg, Beijing 100050, Peoples R China;[2]Capital Univ Med Sci, Beijing Tiantan Hosp, Dept Neurosurg, Tiantan Xili 6, Beijing 100050, Peoples R China
推荐引用方式(GB/T 7714)：
Tang Jie,Ma Zhenyu,Luo Shiqi,et al.The germinomas arising from the basal ganglia and thalamus[J].CHILDS NERVOUS SYSTEM.2008,24(3):303-306.doi:10.1007/s00381-007-0460-0.
APA：
Tang, Jie,Ma, Zhenyu,Luo, Shiqi,Zhang, Yuqi,Jia, Ge&Zhang, Junting.(2008).The germinomas arising from the basal ganglia and thalamus.CHILDS NERVOUS SYSTEM,24,(3)
MLA：
Tang, Jie,et al."The germinomas arising from the basal ganglia and thalamus".CHILDS NERVOUS SYSTEM 24..3(2008):303-306
