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Continuous Beta-Blocker Therapy Delays Structural Deterioration after Bioprosthetic Mitral Valve Replacement.

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机构: [1]Department of Cardiovascular Surgery, Shanghai Chest Hospital, Shanghai, China [2]Zhongshan Hospital Fudan University, Shanghai, China [3]Department of Intensive Care Unit, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, Shanghai, China [4]Center for Cardiac Intensive Care, Beijing Anzhen Hospital, Beijing, China [5]Department of Cardiac Surgery, Huai’an First People’s Hospital, The Affiliated Huai’an No. 1 People’s Hospital of Nanjing Medical University, Huai’an, China
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关键词: mitral valve replacement echocardiography heart valve surgery

摘要:
The impact of continuous beta-blocker (BB) therapy on structural valve deterioration (SVD) after bioprosthetic mitral replacement was investigated. From 2000 to 2005, 138 such patients were propensity score matched in a 1:1 fashion (continuous BB therapy after surgery, n = 69; without BB therapy, n = 69). Median follow-up was 12.3 years. Cardiac mortality was comparable between patients with and without BB therapy (p = 0.13), while the 10-year freedom from SVD was significantly higher in patients with BB therapy (92.4 vs. 76.3%, p = 0.001). In conclusion, continuous BB therapy may be considered in patients after bioprosthetic mitral valve replacement to delay SVD and improve prosthetic durability. Georg Thieme Verlag KG Stuttgart · New York.

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出版当年[2018]版:
大类 | 4 区 医学
小类 | 4 区 心脏和心血管系统 4 区 呼吸系统 4 区 外科
最新[2023]版:
大类 | 4 区 医学
小类 | 4 区 心脏和心血管系统 4 区 呼吸系统 4 区 外科
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第一作者机构: [1]Department of Cardiovascular Surgery, Shanghai Chest Hospital, Shanghai, China [2]Zhongshan Hospital Fudan University, Shanghai, China
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通讯机构: [1]Department of Cardiovascular Surgery, Shanghai Chest Hospital, Shanghai, China [5]Department of Cardiac Surgery, Huai’an First People’s Hospital, The Affiliated Huai’an No. 1 People’s Hospital of Nanjing Medical University, Huai’an, China [*1]Department of Cardiac Surgery, Huai’an First People’s Hospital, The Affiliated Huai’an No. 1 People’s Hospital of Nanjing Medical University, No. 1 West Huanghe Road, Huai’an 223300, China
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