机构:[a]Aortic Institute at Yale-New Haven Hospital, Yale University School of Medicine, New Haven, Conn[b]Department of Political Sciences and Economics, Rowan University, Glassboro, NJ[c]Department of Economics and Department of Preventive Medicine, Stony Brook University, Stony Brook, NY[d]Department of Cardiovascular Surgery, Beijing Anzhen Hospital of Capital Medical University, Beijing, China临床科室心脏外科中心血管科首都医科大学附属安贞医院[e]Department of Vascular Surgery, Yale University School of Medicine, New Haven, Conn[f]Department of Cardiac Surgery, University HospitalMunich, Ludwig Maximilian University, Munich, Germany[g]Department of Surgical Diseases 2, Kazan State Medical University, Kazan, Russia.
Background: In international guidelines, risk estimation for thoracic ascending aortic aneurysm (TAAA) is based on aortic diameter. We previously introduced the aortic size index (ASI), defined as aortic size/body surface area (BSA), as a predictor of aortic dissection, rupture, and death. However, weight might not contribute substantially to aortic size and growth. We seek to evaluate the height-based aortic height index (AHI) versus ASI for risk estimation and revisit our natural history calculations. Methods: Aortic diameters and long-term complications of 780 patients with TAAA were analyzed. Growth rate estimates, yearly complication rates, and survival were assessed. Risk stratification was performed using regression models. The predictive value of AHI and ASI was compared. Results: Patients were stratified into 4 categories of yearly risk of complications based on their ASI and AHI. ASIs (cm/m(2)) of <= 2.05, 2.08 to 2.95, 3.00 to 3.95 and >= 4, and AHIs (cm/m) of <= 2.43, 2.44 to 3.17, 3.21 to 4.06, and >= 4.1 were associated with a 4%, 7%, 12%, and 18% average yearly risk of complications, respectively. Five-year complication-free survival was progressively worse with increasing ASI and AHI. Both ASI and AHI were shown to be significant predictors of complications (P<. 05). AHI categories 3.05 to 3.69, 3.70 to 4.34, and >= 4.35 cm/m were associated with a significantly increased risk of complications (P<. 05). The overall fit of the model using AHI was modestly superior according to the concordance statistic. Conclusions: Compared with indices including weight, the simpler height-based ratio (excluding weight and BSA calculations) yields satisfactory results for evaluating the risk of natural complications in patients with TAAA.
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外文
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中科院(CAS)分区:
出版当年[2017]版:
大类|2 区医学
小类|2 区呼吸系统2 区外科3 区心脏和心血管系统
最新[2023]版:
大类|1 区医学
小类|1 区外科2 区心脏和心血管系统2 区呼吸系统
JCR分区:
出版当年[2016]版:
Q1SURGERYQ1RESPIRATORY SYSTEMQ2CARDIAC & CARDIOVASCULAR SYSTEMS
第一作者机构:[a]Aortic Institute at Yale-New Haven Hospital, Yale University School of Medicine, New Haven, Conn
通讯作者:
通讯机构:[a]Aortic Institute at Yale-New Haven Hospital, Yale University School of Medicine, New Haven, Conn[*1]Aortic Institute at Yale-New Haven, Yale University School of Medicine, Clinic Building CB 317 789 Howard Ave, New Haven, CT 06519
推荐引用方式(GB/T 7714):
Mohammad A. Zafar,Yupeng Li,John A. Rizzo,et al.Height alone, rather than body surface area, suffices for risk estimation in ascending aortic aneurysm[J].JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY.2018,155(5):1938-1950.doi:10.1016/j.jtcvs.2017.10.140.
APA:
Mohammad A. Zafar,Yupeng Li,John A. Rizzo,Paris Charilaou,Ayman Saeyeldin...&John A. Elefteriades.(2018).Height alone, rather than body surface area, suffices for risk estimation in ascending aortic aneurysm.JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY,155,(5)
MLA:
Mohammad A. Zafar,et al."Height alone, rather than body surface area, suffices for risk estimation in ascending aortic aneurysm".JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY 155..5(2018):1938-1950