Clinical Outcomes of Adult Patients Who Receive Extracorporeal Membrane Oxygenation for Postcardiotomy Cardiogenic Shock: A Systematic Review and Meta-Analysis
Objective: To investigate the clinical outcomes of adult patients receiving extracorporeal membrane oxygenation (ECMO) for postcardiotomy cardiogenic shock (PCS). Design: Meta-analysis of 20 observational studies. Setting: Hospitals that perform cardiac surgery. Participants: The study included 2,877 PCS patients undergoing ECMO from 20 observational studies. Interventions: ECMO use. Measurements and Main Results: Twenty observational studies were selected for final analysis. The pooled survival rate to hospital discharge was 34.0% (30.0%-38.0%) in PCS patients receiving ECMO. The pooled 1-year survival rate was 24.0% (19.05%-30.0%). The pooled midterm survival rate was 18.0% (11.0%-27.0%). The pooled rate of leg ischemia was 14.0% (10.0%-20.0%). The pooled rate of redo surgery was 50.0% (32.0%-68.0%). The pooled rate of renal failure was 57.0% (47.0%-66.0%). The pooled rate of neurologic complications was 16.0% (13.0%-20.0%). The pooled rate of infection was 31.0% (22.0%-41.0%). Most of the included studies commonly revealed that age > 65 years, pre-ECMO or post-ECMO blood lactate, renal insufficiency, a longer duration of ECMO, and neurologic complications were risk factors of in-hospital mortality in PCS patients undergoing ECMO. Conclusions: The short-term and midterm survival rates of PCS patients treated with ECMO were disappointingly low, and post-ECMO complication rates were relatively high. (C) 2018 Elsevier Inc. All rights reserved.
基金：
Research Foundation of Capital Medical Development [2014-1-1051]; Beijing Municipal Science and Technology CommissionBeijing Municipal Science & Technology Commission [Z161100000516017]; National Key Research and Development Program of China [2016YFC1301001]
语种：
外文
被引次数：
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PubmedID：
中科院(CAS)分区：
出版当年[2017]版：
大类|4 区医学
小类|4 区麻醉学4 区心脏和心血管系统4 区外周血管病4 区呼吸系统
最新[2023]版：
大类|4 区医学
小类|4 区麻醉学4 区心脏和心血管系统4 区外周血管病4 区呼吸系统
JCR分区：
出版当年[2016]版：
Q3PERIPHERAL VASCULAR DISEASEQ3ANESTHESIOLOGYQ3CARDIAC & CARDIOVASCULAR SYSTEMSQ4RESPIRATORY SYSTEM
Liangshan Wang,HongWang,XiaotongHou.Clinical Outcomes of Adult Patients Who Receive Extracorporeal Membrane Oxygenation for Postcardiotomy Cardiogenic Shock: A Systematic Review and Meta-Analysis[J].JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA.2018,32(5):2087-2093.doi:10.1053/j.jvca.2018.03.016.
APA：
Liangshan Wang,HongWang&XiaotongHou.(2018).Clinical Outcomes of Adult Patients Who Receive Extracorporeal Membrane Oxygenation for Postcardiotomy Cardiogenic Shock: A Systematic Review and Meta-Analysis.JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA,32,(5)
MLA：
Liangshan Wang,et al."Clinical Outcomes of Adult Patients Who Receive Extracorporeal Membrane Oxygenation for Postcardiotomy Cardiogenic Shock: A Systematic Review and Meta-Analysis".JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA 32..5(2018):2087-2093
