机构：[1]Chinese Acad Med Sci, Natl Ctr Cardiovasc Dis, Fu Wai Hosp, Div Dyslipidemia,State Key Lab Cardiovasc Dis, Beijing 100037, Peoples R China;[2]Peking Union Med Coll, Beijing 100037, Peoples R China;[3]Fifth Hosp Wuhan City, Dept Cardiol, Wuhan 430050, Peoples R China;[4]Capital Univ Med Sci, Beijing Anzhen Hosp, Dept Cardiol, Beijing 100029, Peoples R China临床科室心脏内科中心首都医科大学附属安贞医院
Background: Red cell distribution width (RDW) has been recognized as a novel marker for several cardiovascular diseases. The aim of this study was to evaluate the association between RDW levels and the presence of isolated coronary artery ectasia (CAE). Methods: We studied 414 subjects including 113 patients with isolated CAE (Group A), 144 patients with coronary artery disease (CAD, group B) and 157 angiographically normal controls (group C). Baseline clinical characteristics and laboratory findings including RDW were compared among three groups. Results: The levels of RDW were significantly higher in group A and B compared with that in group C (12.97 +/- 1.4 and 12.88 +/- 1.0 vs 12.34 +/- 0.9, p = 0.020) while no difference was found between CAE and CAD (p = 0.17). Additionally, the levels of CRP were also higher in patients with CAE and CAD compared with normal controls (0.26 +/- 0.14 mg/L, 0.31 +/- 0.27 mg/L vs 0.20 +/- 0.06 mg/L, p = 0.04). The multivariate analysis indicated that RDW and CRP were the independent variables most strongly associated with the presence of isolated CAE and CAD. There was a positive correlation between levels of RDW and CRP in patients with isolated CAE (gamma=0.532, p = 0.001). Conclusions: Our data suggested that RDW may be a useful marker and independent predictor for the presence of isolated CAE.
基金：
National Natural Scientific FoundationNational Natural Science Foundation of China [81070171, 81241121, 81100118]; Specialized Research Fund for the Doctoral Program of Higher Education of ChinaSpecialized Research Fund for the Doctoral Program of Higher Education (SRFDP) [20101106120007, 20111106110013]; Capital Special Foundation of Clinical Application Research [Z121107001012015]; Capital Health Development Fund [2011400302]; Beijing Natural Scientific FoundationBeijing Natural Science Foundation [7131014]; Specialized Research Personnel Fund of Fu Wai Hospital [2012-FWXX02]
第一作者机构：[1]Chinese Acad Med Sci, Natl Ctr Cardiovasc Dis, Fu Wai Hosp, Div Dyslipidemia,State Key Lab Cardiovasc Dis, Beijing 100037, Peoples R China;[2]Peking Union Med Coll, Beijing 100037, Peoples R China;
通讯作者：
通讯机构：[1]Chinese Acad Med Sci, Natl Ctr Cardiovasc Dis, Fu Wai Hosp, Div Dyslipidemia,State Key Lab Cardiovasc Dis, Beijing 100037, Peoples R China;[2]Peking Union Med Coll, Beijing 100037, Peoples R China;
推荐引用方式(GB/T 7714)：
Li Xiao-Lin,Hong Li-Feng,Jia Yan-Jun,et al.Significance of red cell distribution width measurement for the patients with isolated coronary artery ectasia[J].JOURNAL OF TRANSLATIONAL MEDICINE.2014,12(1):-.doi:10.1186/1479-5876-12-62.
APA：
Li, Xiao-Lin,Hong, Li-Feng,Jia, Yan-Jun,Nie, Shao-Ping,Guo, Yuan-Lin...&Li, Jian-Jun.(2014).Significance of red cell distribution width measurement for the patients with isolated coronary artery ectasia.JOURNAL OF TRANSLATIONAL MEDICINE,12,(1)
MLA：
Li, Xiao-Lin,et al."Significance of red cell distribution width measurement for the patients with isolated coronary artery ectasia".JOURNAL OF TRANSLATIONAL MEDICINE 12..1(2014):-
医学