Background: Few data can be available regarding acute liver failure (ALF) caused by severe acute hepatitis B up to now. This study aims to report such cases from China. Findings: We conducted a multi-center investigation on ALF from 7 tertiary hospitals in different areas of China. A total of 11 patients with ALF caused by severe acute hepatitis B were finally identified. In these patients, there were 10 male and 1 female patients. As a serious complication, apparent hemorrhage occurred in 9 patients. Eventually, in these 11 patients, 4 survived and 7 died. 4 died of heavy bleeding, 2 died of systemic inflammatory response syndrome and 1 died of irreversible coma. No patients received liver transplantation. Conclusions: ALF caused by severe acute hepatitis B is worthy of formal studies based on its rarity and severity.
第一作者机构：[1]Capital Med Univ, Beijing Anzhen Hosp, Emergency & Crit Care Ctr, Beijing 100029, Peoples R China;
通讯作者：
通讯机构：[2]PLA 302 Hosp, Beijing Hosp 302, Liver Failure Therapy & Res Ctr, Clin Trial Ctr, Beijing 100039, Peoples R China;[4]PLA 302 Hosp, Beijing Hosp 302, Liver Failure Therapy & Res Ctr, Clin Trial Ctr, 100 West Fourth Ring Middle Rd, Beijing 100039, Peoples R China
推荐引用方式(GB/T 7714)：
Wang Chun-ya,Zhao Pan,Liu Wei-wei.Acute liver failure caused by severe acute hepatitis B: a case series from a multi-center investigation[J].ANNALS OF CLINICAL MICROBIOLOGY AND ANTIMICROBIALS.2014,13(1):-.doi:10.1186/1476-0711-13-23.
APA：
Wang, Chun-ya,Zhao, Pan&Liu, Wei-wei.(2014).Acute liver failure caused by severe acute hepatitis B: a case series from a multi-center investigation.ANNALS OF CLINICAL MICROBIOLOGY AND ANTIMICROBIALS,13,(1)
MLA：
Wang, Chun-ya,et al."Acute liver failure caused by severe acute hepatitis B: a case series from a multi-center investigation".ANNALS OF CLINICAL MICROBIOLOGY AND ANTIMICROBIALS 13..1(2014):-
