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J wave is associated with increased risk of sudden cardiac arrest in patients with hypertrophic cardiomyopathy

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机构: [1]Capital Med Univ, Beijing Chao Yang Hosp, Ctr Heart, Beijing 100020, Peoples R China; [2]Capital Med Univ, Beijing An Zhen Hosp, Cardiovasc Ctr, Beijing, Peoples R China; [3]CAMS, Fu Wai Hosp, Cardiovasc Inst, Beijing, Peoples R China; [4]PUMC, Beijing, Peoples R China; [5]Gen Hosp Beijing Command, Dept Cardiol, Beijing, Peoples R China; [6]Capital Med Univ, Beijing Tongren Hosp, Dept Cardiol, Beijing, Peoples R China; [7]Capital Med Univ, Beijing Friendship Hosp, Ctr Heart, Beijing, Peoples R China; [8]China Japan Friendship Hosp, Dept Cardiol, Beijing, Peoples R China; [9]Capital Med Univ, Beijing Chao Yang Hosp, Ctr Heart, 8 Gongtinan Rd, Beijing 100020, Peoples R China
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关键词: Hypertrophic cardiomyopathy sudden cardiac death sudden cardiac arrest J-point elevation J wave ventricular fibrillation ventricular tachycardia

摘要:
Aims A retrospective, case-control study to investigate the J wave, a J-point elevation on resting 12-lead electrocardiograms, as a risk factor for sudden cardiac arrest (SCA) in patients diagnosed with hypertrophic cardiomyopathy (HCM). Methods Patients with HCM and age- and sex-matched healthy control subjects were recruited, and 12-lead electrocardiograms were performed. The prevalence and related characteristics of J waves were assessed. Patients were followed-up for a mean of 47.9 months. Results Patients with HCM (n=345) had significantly higher prevalence of J waves than healthy controls (n=690; 11.6% and 7.1%, respectively). During follow-up, 14 patients with HCM experienced SCA (SCA subgroup). The prevalence of J waves was significantly higher in the SCA subgroup than in the non-SCA subgroup (42.9% and 10.3%, respectively). There were no significant differences between the SCA and non-SCA subgroups in J wave morphology. Conclusion The J wave may be a risk factor for SCA in patients with HCM.

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出版当年[2012]版:
大类 | 4 区 医学
小类 | 4 区 医学:研究与实验 4 区 药学
最新[2023]版:
大类 | 4 区 医学
小类 | 4 区 医学:研究与实验 4 区 药学
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出版当年[2011]版:
Q4 PHARMACOLOGY & PHARMACY Q4 MEDICINE, RESEARCH & EXPERIMENTAL
最新[2023]版:
Q4 MEDICINE, RESEARCH & EXPERIMENTAL Q4 PHARMACOLOGY & PHARMACY

影响因子: 最新[2023版] 最新五年平均 出版当年[2011版] 出版当年五年平均 出版前一年[2010版] 出版后一年[2012版]

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第一作者机构: [1]Capital Med Univ, Beijing Chao Yang Hosp, Ctr Heart, Beijing 100020, Peoples R China;
通讯作者:
通讯机构: [1]Capital Med Univ, Beijing Chao Yang Hosp, Ctr Heart, Beijing 100020, Peoples R China; [9]Capital Med Univ, Beijing Chao Yang Hosp, Ctr Heart, 8 Gongtinan Rd, Beijing 100020, Peoples R China
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