Objective: To investigate the effects of echo time (TE) on diffusion tensor quantification of brain. Methods: Seven Macaca mulatta underwent diffusion tensor MR imaging (DTI) with a series of TEs at 3.0T MR scanners. The diffusion scalars including mean diffusivity (MD), fractional anisotropy (FA), and eigenvalues (λ 1, λ 2 and λ 3) were measured in the region of interest (ROI) at the bilateral posterior limb of internal capsule and the putamen. Pearson correlation coefficients were used to test the relationships between TE and the diffusion scalars. Results: The MD showed positive correlation with TE in gray matter (GM) (P<0.001) but not in white matter (WM) (P>0.05). Both the FA and λ 1 of GM and WM were positively correlated with TE (P<0.001). The λ 2 of GM increased and λ 2 of WM decreased with increasing TE. And the λ 3 were negatively correlated with TE. Conclusion: TE may influence the quantification of diffusion tensor imaging, which should be controlled in multi-center studies.
语种：
外文
第一作者：
第一作者机构：[1]首都医科大学宣武医院放射科，北京100053
通讯作者：
通讯机构：[1]首都医科大学宣武医院放射科，北京100053
推荐引用方式(GB/T 7714)：
秦 文,李坤成,于春水,et al.Effect of echo time on the quantification of diffusion tensor imaging of brain at 3.0T[J].Chinese Journal of Medical Imaging Technology.2008,24(8):
APA：
秦 文,李坤成,于春水&张 帆.(2008).Effect of echo time on the quantification of diffusion tensor imaging of brain at 3.0T.Chinese Journal of Medical Imaging Technology,24,(8)
MLA：
秦 文,et al."Effect of echo time on the quantification of diffusion tensor imaging of brain at 3.0T".Chinese Journal of Medical Imaging Technology 24..8(2008)
