资源类型：
期刊
文章类型：
论著
作者：
Zhao, B[]
*
;
Tan, X[]
;
Yang, H[]
;
Zheng, K[]
;
Li, Z[]
;
Xiong, Y[]
;
Zhong, M[]
;
Zhang, H[]
;
Liang, C[]
;
Shi, H[]
;
XU, J[]
;
Pan, L[]
;
Zhang, X[]
;
Zhu, G[]
;
Deng, J[]
;
机构：
[a]Department of Neurosurgery, The first affiliated hospital of Wenzhou Medical University, Wenzhou, China
[b]Department of Neurosurgery, The affiliated hospital of Guiyang Medical University, Guiyang, China
[c]Beijing Xuanwu Hospital, Capital Medical university, China
首都医科大学宣武医院
[d]China Medical University, China
[e]Harbin Medical University, China
[f]Zhejiang Medical University, China
[g]Wuhan General Hospital of Military Medical University, China
[h]Nanjing General Hospital of Military Medical University, China
[i]West South hospital of the Third Military, Medical University, China
[j]Tangdu Hospital of the Fourth Military Medical University, China
ISSN：
1471-2377
关键词：
Aneurysmal subarachnoid hemorrhage
Definitive management
Outcome
Poor-grade
Predicators
摘要：
Background: Poor-grade aneurysmal subarachnoid hemorrhage (aSAH) is associated with very high mortality and morbidity. Our limited knowledge on predictors of long-term outcome in poor-grade patients with aSAH definitively managed comes from retrospective and prospective studies of small case series of patients in single center. The purpose of the AMPAS is to determine the long-term outcomes in poor-grade patients with different managements within different time after aSAH, and identify the independent predictors of the outcome that help guide the decision on definitive management.Methods/design: The AMPAS study is a prospective, multicenter, observational registry of consecutive hospitalized patients with poor grade aSAH (WFNS grade IV and V). The aim is to enroll at least 226 poor-grade patients in 11 high-volume medical centers (eg, >150 aSAH cases per year) affiliated to different universities in China. This study will describe poor grade patients and aneurysm characteristics, treatment strategies (modality and time of definitive management), hospitalization complications and outcomes evolve over time. The definitive management is ruptured aneurysm treatment. Outcomes at 3, 6, 12 months after the management were measured using the Glasgow Outcome Scale and the Modified Rankin Scale.Discussion: The AMPAS is the first prospective, multicenter, observational registry of poor grade aSAH with any management. This study will contribute to a better understanding of significant predictors of outcome in poor grade patients and help guide future treatment of the worst patients after aSAH. © 2014 Zhao et al.; licensee BioMed Central Ltd.
中科院(CAS)分区：
出版当年[2013]版：
大类
|
3 区
医学
小类
|
3 区
临床神经病学
最新[2023]版：
大类
|
3 区
医学
小类
|
4 区
临床神经病学
第一作者：
Zhao, B
推荐引用方式(GB/T 7714)：
Zhao B,Tan X,Yang H,et al.A Multicenter prospective study of poor-grade aneurysmal subarachnoid hemorrhage (AMPAS): Observational registry study[J].BMC NEUROLOGY.2014,14(1):doi:10.1186/1471-2377-14-86.
APA：
Zhao, B,Tan, X,Yang, H,Zheng, K,Li, Z...&Deng, J.(2014).A Multicenter prospective study of poor-grade aneurysmal subarachnoid hemorrhage (AMPAS): Observational registry study.BMC NEUROLOGY,14,(1)
MLA：
Zhao, B,et al."A Multicenter prospective study of poor-grade aneurysmal subarachnoid hemorrhage (AMPAS): Observational registry study".BMC NEUROLOGY 14..1(2014)
