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Depression, Anxiety, and Apathy in Mild Cognitive Impairment: Current Perspectives.

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收录情况： ◇ SCIE

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机构： [1]Department of Geriatrics, Xuanwu Hospital, Capital Medical University, China National Clinical Research Center for Geriatric Medicine, Beijing, China

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关键词： mild cognitive impairment depression anxiety apathy dementia

摘要：

Objective: Mild cognitive impairment (MCI) is an important risk state for dementia, particularly Alzheimer's disease (AD). Depression, anxiety, and apathy are commonly observed neuropsychiatric features in MCI, which have been linked to cognitive and functional decline in daily activities, as well as disease progression. Accordingly, the study's objective is to review the prevalence, neuropsychological characteristics, and conversion rates to dementia between MCI patients with and without depression, anxiety, and apathy. Methods: A PubMed search and critical review were performed relating to studies of MCI, depression, anxiety, and apathy. Results: MCI patients have a high prevalence of depression/anxiety/apathy; furthermore, patients with MCI and concomitant depression/anxiety/apathy have more pronounced cognitive deficits and progress more often to dementia than MCI patients without depression/anxiety/apathy. Conclusions and Implications: Depression, anxiety, and apathy are common in MCI and represent possible risk factors for cognitive decline and progression to dementia. Further studies are needed to better understand the role and neurobiology of depression, anxiety, and apathy in MCI. Copyright © 2020 Ma.

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出版当年[2019]版：

大类 | 2 区医学

小类 | 2 区老年医学 3 区神经科学

最新[2023]版：

大类 | 2 区医学

小类 | 3 区老年医学 3 区神经科学

JCR分区：

出版当年[2018]版：

Q2 NEUROSCIENCES Q2 GERIATRICS & GERONTOLOGY

最新[2023]版：

Q2 NEUROSCIENCES Q2 GERIATRICS & GERONTOLOGY

影响因子： 4.1 最新[2023版] 4.6 最新五年平均 3.633 出版当年[2018版] 4.492 出版当年五年平均 3.582 出版前一年[2017版] 4.364 出版后一年[2019版]

第一作者：

第一作者机构： [1]Department of Geriatrics, Xuanwu Hospital, Capital Medical University, China National Clinical Research Center for Geriatric Medicine, Beijing, China

通讯作者：

通讯机构： [1]Department of Geriatrics, Xuanwu Hospital, Capital Medical University, China National Clinical Research Center for Geriatric Medicine, Beijing, China

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Depression, Anxiety, and Apathy in Mild Cognitive Impairment: Current Perspectives.