资源类型:
期刊
收录情况:
◇ SCIE
文章类型:
论著
机构:
[a]Department of MRI, Third Medical Center of Chinese, PLA General Hospital, Beijing, 100039, China
[b]Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing, 100053, China
放射科
[c]Department of Pathology, Third Medical Center of Chinese, PLA General Hospital, Beijing, 100039, China
[d]Department of CT, Third Medical Center of Chinese, PLA General Hospital, Beijing, 100039, China
ISSN:
1471-2415
关键词:
Langerhans cell histiocytosis
MRI features
Orbit
摘要:
Background: To investigate the magnetic resonance imaging (MRI) features of orbital Langerhans cell histiocytosis (LCH) to improve diagnostic accuracy. Methods: We retrospectively reviewed clinical manifestations and MRI findings of 23 patients with histopathology-confirmed LCH of the orbit. The findings were evaluated for the following: (a) symptoms, (b) disease duration, (c) location, (d) configuration, (e) margin, (f) MR imaging signal intensity and enhanced performance. Results: Eighteen patients (78%) in our series were male, only five (22%) patients were female, and the mean age at presentation was 6.3 years. The common symptoms include swollen eyelids, exophthalmos, and a palpable mass. Fourteen patients presented with swollen eyelids and/or exophthalmos. Twenty-two cases involved unilateral orbits, and one case involved bilateral orbits. In our study, there was one patient with cough and expectoration, and one patient with polydipsia and polyuria. Lesions were located in the superior or superlateral orbital roof of seventeen patients (74%). Lesions formed masses or irregular shapes. The 12 out of 23 (52.2%) cases appeared heterogeneous isointense and 10 out of 23 (43.5%) cases showed iso-hypointense on T1-weighted imaging, there were 15 out of 23 (65.2%) cases showed hyper-hypointense mixed signals on T2-weighted imaging. 7 cases found patchy hyperintense signal on T1WI, and 11 cases showed markedly hyperintense signal near the edge of lesions on T2WI. After enhancement, 21 out of 23 (91.3%) cases lesions presented marked enhancement at the edges and the surrounding tissues, and with heterogeneous obvious enhancement of the lesion center. Besides, four cases lesions were surrounded by a low circular signal. Conclusion: There were several characteristics MRI features that can provide crucial information for clinicians and improve our understanding and the diagnostic accuracy of the orbital LCH. © 2019 The Author(s).
被引次数:
6
WOS:
WOS:000510605100003
PubmedID:
31856763
中科院(CAS)分区:
出版当年[2018]版:
大类
|
4 区
医学
小类
|
4 区
眼科学
最新[2023]版:
大类
|
4 区
医学
小类
|
3 区
眼科学
JCR分区:
出版当年[2017]版:
Q3
OPHTHALMOLOGY
最新[2023]版:
Q3
OPHTHALMOLOGY
影响因子:
1.7
最新[2023版]
2
最新五年平均
1.77
出版当年[2017版]
1.819
出版当年五年平均
1.586
出版前一年[2016版]
1.431
出版后一年[2018版]
第一作者:
Wu, C
第一作者机构:
[a]Department of MRI, Third Medical Center of Chinese, PLA General Hospital, Beijing, 100039, China
通讯作者:
Mu, X
推荐引用方式(GB/T 7714):
Wu C,Li K,Hei Y,et al.MR imaging features of orbital Langerhans cell Histiocytosis[J].BMC OPHTHALMOLOGY.2019,19(1):263.doi:10.1186/s12886-019-1269-9.
APA:
Wu, C,Li, K,Hei, Y,Lan, P&Mu, X.(2019).MR imaging features of orbital Langerhans cell Histiocytosis.BMC OPHTHALMOLOGY,19,(1)
MLA:
Wu, C,et al."MR imaging features of orbital Langerhans cell Histiocytosis".BMC OPHTHALMOLOGY 19..1(2019):263