机构:[1]Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China,神经科系统神经内科首都医科大学宣武医院[2]The Affiliated Hospital and the Second Clinical Medical College of North Sichuan Medical University, Nanchong Central Hospital, Nanchong, China,[3]National Clinical Research Center for Geriatric Disorders, Beijing, China,[4]Center of Alzheimer’s Disease, Beijing Institute for Brain Disorders, Beijing, China
Since late stage dementia, including Alzheimer's disease (AD), cannot be reversed by any available drugs, there is increasing research interest in the preclinical stage of AD, i.e., subjective cognitive decline (SCD). SCD is characterized by self-perceptive cognitive decline but is difficult to detect using objective tests. At SCD stage, the cognitive deficits can be more easily reversed compared to that of mild cognitive impairment (MCI) and AD only if accurate diagnosis of SCD and early intervention can be developed. In this paper, we review the recent progress of SCD research including current assessment tools, biomarkers, neuroimaging, intervention and expected prognosis, and the potential relevance to traumatic brain injury (TBI)-induced cognitive deficits.
基金:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China [61633018]; affiliated hospital and the second clinical medical college of the North Sichuan Medical University, Nanchong Central Hospital
第一作者机构:[1]Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China,
通讯作者:
推荐引用方式(GB/T 7714):
Si Tong,Xing Guoqiang,Han Ying.Subjective Cognitive Decline and Related Cognitive Deficits[J].FRONTIERS IN NEUROLOGY.2020,11:doi:10.3389/fneur.2020.00247.
APA:
Si, Tong,Xing, Guoqiang&Han, Ying.(2020).Subjective Cognitive Decline and Related Cognitive Deficits.FRONTIERS IN NEUROLOGY,11,
MLA:
Si, Tong,et al."Subjective Cognitive Decline and Related Cognitive Deficits".FRONTIERS IN NEUROLOGY 11.(2020)