Vision impairment, vision correction, and cognitive decline among middle-aged and older Chinese: results from the China health and retirement longitudinal study
机构：[1]Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, China[2]Medical Informatics Center, Peking University Medical Informatics Center, Beijing, China[3]School of Social Work, Texas State University, San Marcos, TX, USA[4]Department of Medicine, Yale School of Medicine, New Haven, CT, USA[5]Department of Ophthalmology, Peking University People’s Hospital, Beijing, China[6]Eye Disease and Optometry Institute, Peking University People’s Hospital, Beijing, China[7]Beijing, Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, Beijing, China[8]College of Optometry, Peking University Health Science Center, Beijing, China[9]Department of Evidence-Based Medicine, Xuanwu Hospital, Capital Medical University, Beijing, China首都医科大学宣武医院循证医学中心
Objectives To investigate the associations between vision impairment (VI), vision correction (VC), and cognitive function. Method We included 20,677 participants aged >= 45 years from the China Health and Retirement Longitudinal Study (2011-2015). Participants were grouped into no VI, distance VI (DVI) only, near VI (NVI) only, or both distance and near VI (DNVI), and VI(+)/VC(-), VI(+)/VC(+), VI(-)/VC(-), or VI(-)/VC(+) further at baseline. Cognitive function at baseline and subsequently every two years was applied as a dependent variable in a generalized estimating equation model. Results DVI only, NVI only, and DNVI had significantly worse cognitive function over time than no VI (allp < .05). DNVI had significantly worse cognitive function over time than DVI only and NVI only (allp < .001). VI(+)/VC(+), VI(-)/VC(-), and VI(-)/VC(+) had significantly better cognitive function over time than VI(+)/VC(-) (allp < .05). VI(-)/VC(+) had significantly better cognitive function over time than VI(+)/VC(+) and VI(-)/VC(-) (allp < .05). Conclusion Cognitive function was worse in middle-aged and older Chinese with VI, especially in those with DNVI. VC was associated with better cognitive function over time regardless of the status of vision.
基金：
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81703304]; Peking University Medicine Seed Fund for Interdisciplinary Research [BMU2018MX003]
第一作者机构：[1]Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, China[2]Medical Informatics Center, Peking University Medical Informatics Center, Beijing, China
通讯作者：
推荐引用方式(GB/T 7714)：
Cao Gui-Ying,Yao Shan-Shan,Wang Kaipeng,et al.Vision impairment, vision correction, and cognitive decline among middle-aged and older Chinese: results from the China health and retirement longitudinal study[J].AGING & MENTAL HEALTH.2021,25(11):2028-2035.doi:10.1080/13607863.2020.1828271.
APA：
Cao, Gui-Ying,Yao, Shan-Shan,Wang, Kaipeng,Han, Ling,Chen, Zi-Shuo...&Xu, Beibei.(2021).Vision impairment, vision correction, and cognitive decline among middle-aged and older Chinese: results from the China health and retirement longitudinal study.AGING & MENTAL HEALTH,25,(11)
MLA：
Cao, Gui-Ying,et al."Vision impairment, vision correction, and cognitive decline among middle-aged and older Chinese: results from the China health and retirement longitudinal study".AGING & MENTAL HEALTH 25..11(2021):2028-2035
