机构：[1]Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China,神经科系统神经内科首都医科大学宣武医院[2]Advanced Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China,[3]Department of China-America Institute of Neuroscience, Xuanwu Hospital, Capital Medical University, Beijing, China,科技平台中美神经科学研究所首都医科大学宣武医院[4]Department of Neurosurgery, Wayne State University School of Medicine, Detroit, MI, United States
This study reported two cases of intracranial thrombotic events of aplastic anemia (AA) under therapy with cyclosporine-A (CsA) and reviewed both drug-induced cerebral venous thrombosis (CVT) and CsA-related thrombotic events systematically. We searched PubMed Central (PMC) and EMBASE up to Sep 2019 for publications on drug-induced CVT and Cs-A-induced thrombotic events. Medical subject headings and Emtree headings were used with the following keywords: "cyclosporine-A" and "cerebral venous thrombosis OR cerebral vein thrombosis" and "stroke OR Brain Ischemia OR Brain Infarction OR cerebral infarction OR intracerebral hemorrhage OR intracranial hemorrhage." We found that CsA might be a significant risk factor in inducing not only CVT but also cerebral arterial thrombosis in patients with AA.
基金：
National Key R&D Program of China [2017YFC1308400]; National Natural Science FoundationNational Natural Science Foundation of China (NSFC) [81371289]; Project of Beijing Municipal Top Talent for Healthy Work of China [2014-2-015]
第一作者机构：[1]Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China,[2]Advanced Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China,[3]Department of China-America Institute of Neuroscience, Xuanwu Hospital, Capital Medical University, Beijing, China,
通讯作者：
推荐引用方式(GB/T 7714)：
Song Si-ying,Wang Zhong-ao,Ding Yu-chuan,et al.Cyclosporine-A-Induced Intracranial Thrombotic Complications: Systematic Review and Cases Report[J].FRONTIERS IN NEUROLOGY.2021,11:doi:10.3389/fneur.2020.563037.
APA：
Song, Si-ying,Wang, Zhong-ao,Ding, Yu-chuan,Ji, Xun-ming&Meng, Ran.(2021).Cyclosporine-A-Induced Intracranial Thrombotic Complications: Systematic Review and Cases Report.FRONTIERS IN NEUROLOGY,11,
MLA：
Song, Si-ying,et al."Cyclosporine-A-Induced Intracranial Thrombotic Complications: Systematic Review and Cases Report".FRONTIERS IN NEUROLOGY 11.(2021)
